Episode 15: Advancing Glycoscience Research: Empowering Discovery with GlyGen

DescriptionIn this podcast, Allissa Dillman talks with Raja Mazumder, René Ranzinger, and Michael Tiemeyer about their journeys in glycoscience and the goals of the GlyGen program. GlyGen integrates glycan and glycoinformatics data from various sources, making it an accessible and comprehensive online resource for researchers. They also discuss the challenges of working with glycan data, including its structural complexity and variability. They cover several workflows using GlyGen resources, how researchers can contribute data to GlyGen and suggestions for new users on how to get started.GuestsRaja Mazumder, PhDRené Ranzinger, PhDMichael Tiemeyer, PhDGuest BiosRaja Mazumder, PhD is a Professor of Biochemistry and Molecular Medicine and Co-Director of The McCormick Genomic Proteomic Center at George Washington University. His background is in evolutionary biology and bioinformatics. He has previously worked at the Oak Ridge National Laboratory, Merck, NIH, and Georgetown University. While working on UniProt at Protein Information Resource, and leading projects such as BioCompute, GlyGen, OncoMX, and ARGOS, Dr. Mazumder worked closely with colleagues in developing international molecular biology resources and using these resources to identify therapeutics, diagnostics and vaccines targets. Through NIH, NSF, FDA and industry funding he is involved in genomic and bioinformatics research in cancer biology, glycobiology, metagenomics and bioinformatics standards development.René Ranzinger, PhD is an Associate Research Scientist in the Complex Carbohydrate Research Centre at the University of Georgia. His work focuses on GlycoBioinformatics. As a research scientist, he worked on the implementation of new software tools for the interpretation of glycomics mass spectrometric data. He and his team were also involved in the design and implementation of glycomics databases such as GlyTouCan and GlyGen. Another focus of his work is the standardization of glycomics data reporting as well as standardization of data representation and data exchange. In this context he was organizer and member of several international working groups including the working group to define minimum reporting standards for Glycomics (MIRAGE). Michael Tiemeyer, PhD, is the Joint Director of the Complex Carbohydrate Research Center and the Center for Molecular Medicine at the University of Georgia, where he facilitates the research programs of 24 active faculty and 300 research trainees and staff who generate between 20-25 million USD in total grants and contracts each year. He also holds the title of Distinguished Research Professor in the Department of Biochemistry and Molecular Biology at the University of Georgia. His own active research areas are focused on the identification and characterization of bioactive glycans in neural development and disease as well as on the development of glycoinformatic strategies and platforms for capturing knowledge in the glycoscience domain.