Episode 15: Cystic Fibrosis Explained: Genetics, Treatment Advances & What Carrier Screening Really Means (with Prof John Massie)

Cystic fibrosis (CF) is one of the most common inherited, life-shortening childhood conditions — but its story is changing.In this episode, Ali is joined by Professor John Massie, respiratory physician and CF specialist, to unpack what cystic fibrosis is, how it affects the body, and how advances in treatment are transforming outcomes for many people living with CF.Together, they explore:How CF is inherited and why carrier screening mattersWhat day-to-day life with CF can look like, from infancy to adulthoodThe impact of modern CFTR modulator therapies and who can benefitWhy newborn screening and reproductive carrier screening play different and complementary rolesHow families experience diagnosis, decision-making, and care pathwaysThis conversation is designed for clinicians, prospective parents, and anyone seeking a clear and comprehensive explanation of cystic fibrosis in today’s clinical landscape.