Episode 157: Why Weight Regain Happens After Weight Loss Medications episode artwork

EPISODE · Jan 25, 2026 · 32 MIN

Episode 157: Why Weight Regain Happens After Weight Loss Medications

from Eating For You · host Sallyanne Pisk

Weight loss medications like Ozempic, Wegovy and Mounjaro are everywhere right now—and if you’re curious about them (or taking one), there’s nothing wrong with you.In Episode 157, as a non-diet, mindfulness-based dietitian, I unpack what the research shows about weight regain after stopping weight loss medications and why regain is often biological, not a personal failure. You’ll learn how GLP-1 medications work, the side effects people don’t always understand, and why focusing on body composition (muscle vs fat) matters more than a number on the scale.You’ll also hear a research-based comparison of regain after medication versus regain after lifestyle and behavioural programs—including why long-term support, resistance-based movement and personalised nourishment can make a difference.In this episode:How GLP-1 medications work (appetite suppression + regulation)Why side effects can unintentionally reduce protein intake and movementWhat a 2025 systematic review found about weight regain after stopping medicationWhy muscle preservation changes the whole storyMedication regain vs lifestyle-program regain: timelines and what’s differentA more realistic question: is it even helpful to expect a stable weight across life stages?✨ Free support: Book a complimentary 30-minute Mindful Eating Strategy Call📩 Subscribe to the Nourishment newsletter so you receive all updates and tips to help you sustain healthy eating for goodSUBSCRIBE to the Eating for You podcast so you don't miss any episodes x

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Episode 157: Why Weight Regain Happens After Weight Loss Medications

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