Episode #173. What We Don’t Know: Leading AI Governance with Humility and Clarity, with  Anahi Santiago, Chief Information Security Officer at ChristianaCare episode artwork

EPISODE · Dec 22, 2025 · 23 MIN

Episode #173. What We Don’t Know: Leading AI Governance with Humility and Clarity, with Anahi Santiago, Chief Information Security Officer at ChristianaCare

from Risk Never Sleeps Podcast · host Ed Gaudet

This episode of the AI Med 25 Insights series is brought to you by Outcomes Rocket and Censinet. AI is advancing rapidly in healthcare, but what happens behind the scenes when a system attempts to adopt it responsibly? In this episode, Anahi Santiago, Chief Information Security Officer at ChristianaCare, shares how a tech-forward health system is embracing AI across clinical workflows, operations, and cybersecurity. She explains the governance rubric they’ve created to assess every new use case and the challenge of keeping pace with teams eager to deploy AI without fully grasping the clinical, ethical, and operational risks. Anahi emphasizes the importance of shared risk ownership and equal voices across departments as the organization navigates the unknowns in a rapidly evolving landscape. She also reflects on how tools like Copilot boost productivity and how new guidance from the Healthcare Sector Coordinating Council will shape her next steps. If you want to hear how one of the nation’s most forward-leaning CISOs is steering AI innovation with clarity and candor, tune in! Connect with and follow Anahi Santiago on LinkedIn. Follow ChristianaCare on LinkedIn and visit their website! For more information and ways to increase risk awareness and safety, visit us at⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.censinet.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. Music by⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠David Cosgrove⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ an accomplished composer, musician, producer, and engineer. Listen to his latest project⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Del Piombo⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.

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Episode #173. What We Don’t Know: Leading AI Governance with Humility and Clarity, with Anahi Santiago, Chief Information Security Officer at ChristianaCare

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