Episode 22: Rapamycin – The fountain of youth?

Rapamycin was first shown to extend the lifespan of wild-type mice in 2009 by the National Institute on Aging Interventions Testing Program, and since that time, numerous studies in mice of different genetic backgrounds by many independent laboratories have confirmed the strong prolongevity effect of rapamycin. Finally, and most dramatically, rapamycin has been reported to actually reverse aging, rejuvenating tissues including the aging heart as well as hematopoietic stem cells.