Episode 25 - Alphabet Soup | Overview of Myeloma Treatments

from Bloody Minded · host Bloody Minded Crew

RVd, KTd, CyBorD, DVd, EloRd - Looks like the cat got on the keyboard. Oh wait, this is just the myeloma regimens in day therapy today. Come on a journey as we attempt (mostly successfully) to avoid drug trade names! Let go of your proteasome inhibitions, phenotype your red cells and let us modulate your understanding of what it is to treat myeloma with an alphabet soups worth of drugs. We sincerely apologise to our endocrinology colleagues for how much dexamethasone we use in this episode but also generally. Timestamps4:00 - Overview of the treatment journey9:49 - Steroids - not the bulking kind13:54 - Immunomodulators - the IMiDs19:46 - Proteasome inhibitors - Bortezomib, Carflizomib24:45 - Monoclonal antibodies - Daratumumab, Elotuzumab28:31 - SINE Inhibitor - Selinexor29:27 - Antibody-drug conjugates - Belantamab mafodotin30:27 - CELMoDs - Iberdomide, mezigdomide31:06 - Standard chemotherapy33:15 - Autologous stem cell transplant38:21 - T-cell directed therapy - BiTes, CAR-T40:57 - Supportive careSupport the showCheck out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

Episode metadata supplied by the publisher feed · Published Nov 26, 2024

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Episode 25 - Alphabet Soup | Overview of Myeloma Treatments

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