Episode 26: Dr. Jessica Rose on Modified MRNA In Covid-19 Vaccines episode artwork

EPISODE · Jan 15, 2024 · 1H 17M

Episode 26: Dr. Jessica Rose on Modified MRNA In Covid-19 Vaccines

from The Illusion of Consensus · host Jay Bhattacharya and Jessica Rose

Hi everyone,I’m delighted to have on molecular biologist and fellow freedom fighter on the podcast today. In this conversation, we discuss a new Nature paper that highlights the potential problems with the modified mRNA used in the COVID-19 vaccines. Dr. Rose explain the process of mRNA and protein translation, as well as the role of codon optimization. The conversation delves into the implications of N1-methyl pseudouridine and frame shifting, which can lead to the production of unintended proteins. We also discuss the unpredictability of dosing and the need for further research to understand the potential risks associated with the modified mRNA vaccines.Chapters00:00 Introduction and Background07:05 Discussion on COVID Work08:34 Introduction to the Nature Paper09:01 mRNA and Protein Translation13:25 Modified mRNA and Protein Production29:24 N1-methyl Pseudouridine and Frame Shifting36:05 Discussion on the Nature Paper45:37 Implications and Unknowns52:04 Predictability and Dosing53:01 Codon Optimization and Slippery Sequences54:56 Codon Optimization and Protein Production55:54 Implications of Increasing GC Content56:49 Ribosomal Pausing and Frame Shifting59:08 Co-Translational Folding01:00:06 The Potential of the mRNA Platform01:01:31 The Complexity of the Human Body01:03:17 Safety and Regulatory Considerations01:05:40 Challenges of Coding Different Proteins01:07:01 The Need for Regulatory Processes01:09:21 Takeaways and Implications This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.illusionconsensus.com/subscribe

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Episode 26: Dr. Jessica Rose on Modified MRNA In Covid-19 Vaccines

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