Episode 291 - Concussion science, assessment frameworks and biomarkers

Concussions are a serious issue for everyone from the largest professional leagues to the weekend amateurs. The CDC has released some updated guidelines for assessing concussions and we dive into some new tests to help take the decision out of players hands and back it up with some sound evidence.  Angela Lumba-Brown, David W. Wright, Kelly Sarmiento, Debra Houry. Emergency Department Implementation of the Centers for Disease Control and Prevention Pediatric Mild Traumatic Brain Injury Guideline Recommendations. Annals of Emergency Medicine, 2018; DOI: 10.1016/j.annemergmed.2018.03.045 Johnson VE, Stewart W, Smith DH. Axonal pathology in traumatic brain injury. Experimental Neurology. 246: 35-43 (2013). Ling H, Hardy, J, Zetterberg H. Neurological consequences of traumatic brain injuries in sports. Molecular and Cellular Neuroscience. 66(B): 114-122 (2015). Alexander M. Weber, Anna Pukropski, Christian Kames, Michael Jarrett, Shiroy Dadachanji, Jack Taunton, David K. B. Li, Alexander Rauscher. Pathological Insights From Quantitative Susceptibility Mapping and Diffusion Tensor Imaging in Ice Hockey Players Pre and Post-concussion. Frontiers in Neurology, 2018; 9 DOI: 10.3389/fneur.2018.00575 Pashtun Shahim, Yelverton Tegner, Niklas Marklund, Kaj Blennow, Henrik Zetterberg. Neurofilament light and tau as blood biomarkers for sports-related concussion. Neurology, 2018; 10.1212/WNL.0000000000005518 DOI: 10.1212/WNL.0000000000005518