EPISODE 3: The Gut Barrier—Leaky Gut in a Plastic World

Your gut lining is supposed to act like a filter.It allows nutrients in—and keeps harmful substances out.This barrier is held together by structures called tight junctions.Microplastics appear to interfere with this system.They can trigger inflammation and oxidative stress, weakening the integrity of the gut lining.This leads to increased intestinal permeability—commonly referred to as “leaky gut.”When that happens, unwanted particles can enter the bloodstream.This activates the immune system.And over time, this low-grade inflammation can contribute to chronic symptoms.Next—we connect this directly to the brain.https://us.fullscript.com/welcome/jde-guzman/store-starthttps://www.optimantra.com/optimus/patient/patientaccess/servicesall?pid=N0d1aDU4MFdMMlJCQmc5QmdJYzBZQT09&lid=TWt0aVhmYUtySUJaWk04RzJlZkJiQT09Sources:⁠Detection of various microplastics in human stool: a prospective case series⁠. Annals of Internal Medicine, 2019⁠Impact of microplastics and nanoplastics on liver health: current understanding and future research directions⁠. World Journal of Gastroenterology, 2024⁠Impact of microplastics on the human gut microbiome: a systematic review of microbial composition, diversity, and metabolic disruptions⁠. BMC Gastroenterology, 2025Creative Commons — Attribution 3.0 Unported  — CC BY 3.0 Music promoted by Copyright Free Music - Background Music For Videos 👉⁠    / @podcastbackgroundmusic⁠