Episode 3 - Waiting for Clot(-o) | Prolonged Clotting Times and Anticoagulants episode artwork

EPISODE · May 28, 2024 · 47 MIN

Episode 3 - Waiting for Clot(-o) | Prolonged Clotting Times and Anticoagulants

from Bloody Minded · host Bloody Minded Crew

 “Have you not done tormenting me with your accursed time?“ Senior scientists Vladimir and Estragon are waiting quite a while for a clot to form in their tube. How should you react to prolonged clotting times? We cover an approach to prolonged PT and aPTT, as well as discuss the mechanism of common anticoagulants and their impact on these basic tests.  Timestamps00:00 - Intro01:22 - Episode 2 Recap 03:13 - Why clotting times prolong 05:38 - Short clotting times 07:00 - Platelets and clotting times08:00 - Introduction to Anticoagulants10:25 - Unfractionated Heparin17:04 - Low Molecular Weight Heparins20:20 - Fondaparinux21:37 - Vitamin K "Inhibitors"27:55 - Direct Oral Anticoagulants33:04 - Anticoagulants Recap34:10 - An approach to long clotting times35:58 - Cases45:45 - TakehomesSupport the showCheck out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

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“Have you not done tormenting me with your accursed time?“ Senior scientists Vladimir and Estragon are waiting quite a while for a clot to form in their tube. How should you react to prolonged clotting times? We cover an approach to prolonged PT and aPTT, as well as discuss the mechanism of common anticoagulants and their impact on these basic tests. Timestamps 00:00 - Intro 01:22 - Episode 2 Recap 03:13 - Why clotting times prolong 05:38 - Short clotting times ...

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Episode 3 - Waiting for Clot(-o) | Prolonged Clotting Times and Anticoagulants

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