Episode 30: Medicinal Mushrooms Explained: Gut, Brain & Immune Health with Dr Anna Sitkoff episode artwork

EPISODE · Mar 18, 2026 · 56 MIN

Episode 30: Medicinal Mushrooms Explained: Gut, Brain & Immune Health with Dr Anna Sitkoff

from Gutsy Talks

Medicinal mushrooms are everywhere right now, but what do they actually do, how do they work in the body, and how do you know what’s worth taking?In this episode, I’m joined by Dr Anna Sitkoff, a naturopathic doctor, author, and Chief Science Officer & Co-Founder of Lucidum Medicinals. Dr Anna is a leading expert in medicinal mushrooms and is passionate about making the science behind them practical, evidence-based, and easy to apply in everyday life.As a clinician, Dr Anna supports patients using an integrative approach that combines nutrition, botanicals, medicinal mushrooms, and lifestyle strategies. In this conversation, we break down the real benefits of medicinal mushrooms, particularly for gut health, brain function, nervous system support, and immune balance, while cutting through the hype and misinformation.If you’ve been curious about medicinal mushrooms but unsure where to start (or what to trust), this episode will give you clarity and confidence.In this episode, we chat about:What qualifies a mushroom as “medicinal”The difference between medicinal, culinary, and psychedelic mushroomsHow Lion’s Mane supports the nervous system and cognitionThe science behind nerve regeneration and brain healthLesser-known mushrooms for mood, focus, and resilienceHow medicinal mushrooms interact with the gut microbiomeUsing mushrooms in gut-related conditionsReishi vs Chaga — key differences and when to use eachImmune stimulation vs immune modulationWhat to look for in a high-quality mushroom supplementCommon dosage mistakes and self-prescribing pitfallsContraindications and when extra care is neededCommon myths about medicinal mushroomsDr Anna’s #1 tip for getting started safelyRachel’s (she/her) details: Ready To Take Your Next Step To Support Your Gut?Follow Rachel on Instagram HEREWatch the FREE Masterclass 'How To Overcome Bloating and IBS Naturally' HERE Check out the range of FREE gut health resources HERE Work with Rachel HERE Connect with Dr. Anna (she/her)Connect with Dr. Anna on InstagramVisit Dr. Anna's WebsiteVisit the Lucidum Medicinals WebsiteSupport the showDisclaimer: The information provided on Gutsy Talks is for education and informational purposes only. It is not provided nor intended to substitute for professional advice or care. Please seek the advice of a qualified health care professional in the event you have questions or concerns about your health.

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Medicinal mushrooms are everywhere right now, but what do they actually do, how do they work in the body, and how do you know what’s worth taking? In this episode, I’m joined by Dr Anna Sitkoff, a naturopathic doctor, author, and Chief Science Officer & Co-Founder of Lucidum Medicinals. Dr Anna is a leading expert in medicinal mushrooms and is passionate about making the science behind them practical, evidence-based, and easy to apply in everyday life. As a clinician, Dr Anna supports pat...

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Episode 30: Medicinal Mushrooms Explained: Gut, Brain & Immune Health with Dr Anna Sitkoff

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