Episode 30: The Connection Between your Gut and the Brain

Have you ever thought about why some feelings might be described as gut-wrenching? Or why do the first feelings of love make you feel butterflies in the stomach? It's time to explore how your gut and your brain are connected!Please rate, review, and subscribe and if you have any questions, comments, concerns, queries, or complaints, please email me at [email protected] or DM me at NeuroscienceAmateurHour on Instagram.Also if you have the means/desire to financially support this podcast - please go to https://www.buymeacoffee.com/neuroscienceI really appreciate it!!!Citations and relevant papers are below!Enteric nervous system. qbi.uq.edu.au. Published October 15, 2018. Accessed May 22, 2023. https://qbi.uq.edu.au/brain/brain-anatomy/peripheral-nervous-system/enteric-nervous-system#:~:text=The%20enteric%20nervous%20system%20neuronsCleveland Clinic. Cranial Nerves: Function, Anatomy and Location. Cleveland Clinic. Published October 27, 2021. https://my.clevelandclinic.org/health/body/21998-cranial-nervesMayer EA. Gut feelings: the emerging biology of gut–brain communication. Nature Reviews Neuroscience. 2011;12(8):453-466. doi:https://doi.org/10.1038/nrn3071Carabotti M, Scirocco A, Maselli MA, Severi C. The gut-brain axis: interactions between enteric microbiota, central and enteric nervous systems. Annals of gastroenterology. 2015;28(2):203-209.Oligschlaeger Y, Yadati T, Houben T, Condello Oliván CM, Shiri-Sverdlov R. Inflammatory Bowel Disease: A Stressed “Gut/Feeling.” Cells. 2019;8(7):659. doi:https://doi.org/10.3390/cells8070659Vancamelbeke M, Vermeire S. The intestinal barrier: a fundamental role in health and disease. Expert Review of Gastroenterology & Hepatology. 2017;11(9):821-834. doi:https://doi.org/10.1080/17474124.2017.1343143Clapp M, Aurora N, Herrera L, Bhatia M, Wilen E, Wakefield S. Gut microbiota’s effect on mental health: the gut-brain axis. Clinics and Practice. 2017;7(4). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641835/‌Zoppi S, Madrigal JLM, Pérez-Nievas BG, et al. Endogenous cannabinoid system regulates intestinal barrier function in vivo through cannabinoid type 1 receptor activation. Am J Physiol Gastr L 2012;302:565.Radjabzadeh D, Bosch JA, Uitterlinden AG, et al. Gut microbiome-wide association study of depressive symptoms. Nature Communications. 2022;13(1):7128. doi:https://doi.org/10.1038/s41467-022-34502-3Wapner J. The link between our food, gut microbiome and depression. Washington Post. https://www.washingtonpost.com/wellness/2023/01/31/gut-microbiome-anxiety-depression/. Published January 31, 2023.Fond G, Loundou A, Hamdani N, et al. Anxiety and depression comorbidities in irritable bowel syndrome (IBS): a systematic review and meta-analysis. European Archives of Psychiatry and Clinical Neuroscience. 2014;264(8):651-660. doi:https://doi.org/10.1007/s00406-014-0502-zWhat’s the Difference Between Probiotics and Prebiotics? www.sclhealth.org. https://www.sclhealth.org/blog/2019/07/difference-between-probiotics-and-prebiotics/Liu RT, Walsh RFL, Sheehan AE. Prebiotics and probiotics for depression and anxiety: A systematic review and meta-analysis of controlled clinical trials. Neuroscience & Biobehavioral Reviews. 2019;102:13-23. doi:https://doi.org/10.1016/j.neubiorev.2019.03.023Doll JPSupport the show