Episode 452 - Eureka Prizes 21 - Fighting back against viruses

We celebrate the winners of the Eureka Prizes in 2021. The top prizes in Aussie Science shows that it's possible for major science awards to not be male dominated.  Are humans just the collateral damage of the war between cholera and protozoa? How does getting eaten actually make cholera stronger? We celebrate the achievements of Australian scientists helping make rotavirus vaccines more accessible for all. Producing vaccines cheaply and locally, that are easy to roll out can save half a million lives each year. Whilst vaccines for rotavirus exist already they are complex and costly. Aussie researchers are helping make it simpler and widely available. References: Gustavo Espinoza-Vergara, Parisa Noorian, Cecilia A. Silva-Valenzuela, Benjamin B. A. Raymond, Christopher Allen, M. Mozammel Hoque, Shuyang Sun, Michael S. Johnson, Mathieu Pernice, Staffan Kjelleberg, Steven P. Djordjevic, Maurizio Labbate, Andrew Camilli, Diane McDougald. Vibrio cholerae residing in food vacuoles expelled by protozoa are more infectious in vivo. Nature Microbiology, 2019; DOI: 10.1038/s41564-019-0563-x Bines, J., At Thobari, J., Satria, C., Handley, A., Watts, E., & Cowley, D. et al. (2018). Human Neonatal Rotavirus Vaccine (RV3-BB) to Target Rotavirus from Birth. New England Journal Of Medicine, 378(8), 719-730. doi: 10.1056/nejmoa1706804 Mannix, L. (2021). Eureka science prizes go to childhood vaccine and microplastics hotspot hunt. Retrieved 9 October 2021, from https://www.smh.com.au/national/childhood-vaccine-microplastics-hotspot-hunt-take-top-science-gongs-20211007-p58xyi.html Protozoans and pathogens make for an infectious mix. (2021). Retrieved 9 October 2021, from https://www.uts.edu.au/news/health-science/protozoans-and-pathogens-make-infectious-mix Tu, J. (2021). Meet the women transforming science in Australia: Eureka Prize finalists. Retrieved 9 October 2021, from https://womensagenda.com.au/latest/meet-the-women-transforming-science-in-australia-eureka-prize-finalists/