Episode 463: Insulin, Leptin, and Cortisol: The Triple Threat to Metabolic Success episode artwork

EPISODE · Sep 29, 2025 · 49 MIN

Episode 463: Insulin, Leptin, and Cortisol: The Triple Threat to Metabolic Success

from Naturally Nourished · host Ali Miller RD

In this episode of the Naturally Nourished Podcast, we focus on three key hormones that can significantly impact metabolism: insulin, leptin, and cortisol. Each of these hormones plays an essential role in regulating energy, hunger, and stress, and when imbalances occur, they may be the underlying cause of a metabolic stall or plateau. The conversation explores how insulin resistance can block fat burn, how leptin resistance can interfere with satiety signals, and how cortisol dysregulation can drive cravings and fat storage. We discuss practical strategies for identifying when these hormones are out of balance, along with food-as-medicine approaches, lifestyle modifications, and targeted supplementation to help restore harmony and support optimal metabolic function. Also in this episode:  Join our Keto Reset Program Naturally Nourished Kids Book Tour Events Insulin Naturally Nourished Episode 459 Why Insulin Matters Improved Skeletal Muscle Insulin Sensitivity Study Rapid Reduction in Insulin Resistance Markers Study Leptin Naturally Nourished Episode 146 Keto as a Hormetic Stressor and Leptin  Naturally Nourished Episode 356 Low Fat Keto for Leptin Resistance What is Leptin and why it matters High vs. Low Leptin Leptin, Obesity, and Leptin Resistance: Where Are We 25 Years Later? Ideal range for leptin 5-10 Cortisol Metabolic and blood sugar impact The Anti-Anxiety Diet Adrenal Rehab Program Calm and Clear Relax and Regulate Adaptogen Boost How a Keto Reset Supports Insulin, Leptin & Cortisol Regulation   This episode is sponsored by:  According to extensive research by the Environmental Working Group, virtually every home in America has harmful contaminants in its tap water. That’s why you’ve got to check out AquaTru. AquaTru purifiers use a 4-stage reverse osmosis purification process, and their countertop purifiers work with NO installation or plumbing. It removes 15x more contaminants than ordinary pitcher filters and are specifically designed to combat chemicals like PFAS in your water supply. Naturally Nourished Podcast listeners can use code ALIMILLERRD at AquaTru.com to save 20% off. 

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Episode 463: Insulin, Leptin, and Cortisol: The Triple Threat to Metabolic Success

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