Episode 468: Sulforaphane episode artwork

EPISODE · Nov 3, 2025 · 40 MIN

Episode 468: Sulforaphane

from Naturally Nourished · host Ali Miller RD

Have you heard of sulforaphane? Want to know how to harness the benefits of this powerful compound? Tune in to learn all about sulforaphane—a powerhouse phytonutrient that activates detox and antioxidant pathways to protect your cells.  In this episode, we will unpack how this potent compound supports the body’s natural defense systems, working through the NRF2 pathway to reduce oxidative stress, enhance cellular detoxification, and promote resilience against modern day toxin exposure. We also discuss how food preparation impacts sulforaphane yield, why gut health matters for its conversion, and how to maximize levels through broccoli sprouts, seed extracts, and targeted supplementation.  We also unveil the exciting reformulation of Cellular Antiox, featuring clinically validated broccoli seed extract for enhanced cellular protection alongside glutathione support! Also in this episode:  Shop NEW Cellular Antiox with code CELLULAR15 Naturally Nourished Academy - Now Enrolling with Early Bird Pricing!  What is sulforaphane? Who can benefit from sulforaphane? Sulforaphane in the research Randomized Phase II Clinical Trial of Sulforaphane in Former Smokers at High Risk for Lung Cancer - PubMed Rapid and Sustainable Detoxication of Airborne Pollutants by Broccoli Sprout Beverage: Results of a Randomized Clinical Trial in China - PMC Sulforaphane-rich broccoli sprout extract improves hepatic abnormalities in male subjects - PubMed Effects of broccoli sprout supplements enriched in glucoraphanin on liver functions in healthy middle-aged adults with high-normal serum hepatic biomarkers: A randomized controlled trial Long-lasting beneficial effects of maternal intake of sulforaphane glucosinolate on gut microbiota in adult offspring - ScienceDirect Broccoli or Sulforaphane: Is It the Source or Dose That Matters? - PMC Sulforaphane treatment of autism spectrum disorder (ASD) | PNAS Prep and cooking to maximize sulforaphane Why the gut microbiome matters Probiotic Challenge Protocol How to get sulforaphane in the diet Considerations for BroccoDetox New Cellular Antiox Formulation Setria® Glutathione (250 mg): Clinically studied, reduced form, ready to use N-Acetylcysteine (1,000 mg): A powerful precursor, provides cysteine to fuel internal glutathione production Broccoli Seed Extract 40mg (2mg glucoraphanin): Activates Nrf2 pathway, upregulates endogenous antioxidant production, including glutathione Vitamin B6 (5 mg): Essential cofactor for amino acid metabolism and methylation, supports efficient detox and glutathione recycling New bovine gelatin capsule with silica as an added feature!   Sponsors for this episode:  This episode is sponsored by FOND Bone Broth, your sous chef in a jar. FOND’s bone broths and tallows are produced in small batches with premium ingredients from verified regenerative ranches. Their ingredients are synergistically paired for maximum absorption, nutritional benefit, and flavor. Use code NATURALLY to save at fondbonebroth.com 

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Episode 468: Sulforaphane

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