Episode 49 - In The Lab: Easy as 1-2-3 | Performing a FBC episode artwork

EPISODE · Jun 17, 2025 · 50 MIN

Episode 49 - In The Lab: Easy as 1-2-3 | Performing a FBC

from Bloody Minded · host Bloody Minded Crew

Learning to count is hard. Learning to count cells is harder. Luckily we've got an expert with us today to show us the basics. Welcome back to a new batch of episodes where we unpack the highs and lows of haematology and teach you what to do with those pesky out of range blood counts. But to do that we need to know where the numbers come from. We don't know, so we asked Mitchell Rawlings a senior scientist in haematology to come along and relieve of us of our ignorance. Mitch takes us through automated analysers, the principles of cell counting, and some of those mysterious other acronyms on the full blood count. TIMESTAMPS1:25 - A year in review3:09 - Haematology Made Simple4:04 - Everyone deals with FBCs...4:52 - Mitch Rawlings5:48 - God that intro segment was long9:47 - FBC Stats10:19 - Three Letter Acronym Time13:57 - FBC Journey from Vein to Screen15:30 - Analyser Magic16:40 - Coulter principle17:56 - Ghosts in the machine19:40 - The Differential21:25 - Red Flags24:43 - Haemoglobin measurement - productive destruction26:46 - The lab doesn't hate you - please send enough blood28:53 - Retics all day long30:07 - Derived, measured, calculated parameters32:15 - QC + Drift Controls34:06 - Wrong blood in tube36:29 - Platelet counting - citrated, manual counts40:14 - Mixing "studies" - really bad for FBC42:08 - The problem with aspirating clotsSupport the showCheck out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

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Learning to count is hard. Learning to count cells is harder. Luckily we've got an expert with us today to show us the basics. Welcome back to a new batch of episodes where we unpack the highs and lows of haematology and teach you what to do with those pesky out of range blood counts. But to do that we need to know where the numbers come from. We don't know, so we asked Mitchell Rawlings a senior scientist in haematology to come along and relieve of us of our ignorance. Mitch takes us t...

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Episode 49 - In The Lab: Easy as 1-2-3 | Performing a FBC

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