Episode 5 - The PATHWAYS Trial

Laura wants more data about the effectiveness of puberty blockers. Yvette has seen enough They disagree about most things, but they've agreed to talk about it In this episode, they do a comprehensive review of the recently launched UK Pathways Trial, which seeks to determine if puberty blockers have a role to play in the management of young people with gender incongruence. However, many question have been raised about its design, whether it is ethical, or whether it is even necessary. Plus stay tuned to the end for a special Easter Egg!

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This episode is 1 hour and 3 minutes long.

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This episode was published on March 13, 2026.

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