Episode 6: The Four Generations of HRT and Their Clinical Track Records episode artwork

EPISODE · Oct 10, 2025 · 58 MIN

Episode 6: The Four Generations of HRT and Their Clinical Track Records

from MeNoPause Moxie Podcast · host Marie Hoäg

If your HRT worked for a while and then stopped, you’re not alone.For decades, women have been handed low-dose, short-term hormone therapies that were never designed for full restoration — only to manage symptoms just enough to keep them quiet for a while. And when women speak up that their HRT is no longer working, they are prescribed drugs and sold supplements to manage the side effects of hormone deficiencies they still experience.In this week’s episode of the MeNoPause Moxie Podcast, I reveal what most women (and even many doctors) don’t realize: there are distinct generations of HRT systems, each built with different intentions and results. Understanding the differences can change how you age, how you feel, how you behave — and your susceptibility to mental illness.You’ll Learn* Why so many women are unknowingly kept in a state of estrogen starvation—even while on HRT.* How to tell when your current therapy has reached its limit.* What separates symptom management from true hormone restoration.* Why “low dose” isn’t the same as “safe”—and how it may actually accelerate hormonal decline.· What true hormone restoration looks like — and why it feels completely different.· How therapeutic adaptive dosing brings women into their Hormone Sweet Spot™.Why This Matters for WomenWomen in their 40s, 50s, and beyond are running companies, managing family, leading teams, and building legacies — often while battling brain fog, fatigue, and mood swings caused by chronic hormone deficiency.You deserve more than temporary relief. You deserve a system that restores your full capacity to think, lead, create, and thrive.The more you know how HRT works and what you need, the more control you will have over how your brain and body function and age. This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit menopausemoxie.substack.com

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Episode 6: The Four Generations of HRT and Their Clinical Track Records

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