EPISODE · Sep 16, 2025 · 53 MIN
Episode 61 - On The Wards: BiTE Me and other T Cell Tasty Treats
from Bloody Minded · host Bloody Minded Crew
Have you stumbled onto the haematology ward only to discover patients on bizarrely named BiTE & CART therapy? Why are we giving patients CARTs? Do they come with a horse? Why does everyone freak out when these patients are febrile? Why is everyone so hung up about handwriting? What are these weird drugs? It's OK – we are here once more to demystify the acronyms – and help you know what we are giving, why we are giving it and how to manage complications of Bi-Specific and CAR-T therapy! TIMESTAMPS3:48 - Intro to BiTEs 5:26 - Intro to CAR-T 8:27 - Examples of BiTEs 16:36 - CAR-T Collection + Production 18:44 - Examples of CAR-T Products 19:35 - Similarities and Differences between BiTEs and CAR-T 23:24 - Cytokine Release Syndrome (CRS) 30:23 - Immune Effector Cell-Associated Neurotoxicity Syndrome (ICANS) 39:29 - Treatments for CRS 45:52 - Treatments for ICANS 50:01 - Take Home Messages Support the showCheck out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au
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Have you stumbled onto the haematology ward only to discover patients on bizarrely named BiTE & CART therapy? Why are we giving patients CARTs? Do they come with a horse? Why does everyone freak out when these patients are febrile? Why is everyone so hung up about handwriting? What are these weird drugs? It's OK – we are here once more to demystify the acronyms – and help you know what we are giving, why we are giving it and how to manage complications of Bi-Specific and CAR-T...
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Episode 61 - On The Wards: BiTE Me and other T Cell Tasty Treats
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