Episode 76: Why You Feel Tired But Wired in Your 40s: Cortisol Rhythms Explained

from Empowered Perimenopause With Francesca Liparoti · host Francesca Liparoti

Why do so many women feel exhausted in the morning but wired at night during their 40s? In this episode, Francesca explains how cortisol rhythms change in perimenopause and how stress affects your hormones, thyroid, sleep and digestion. You'll learn: What cortisol actually does in the body The daily cortisol rhythm your body is designed to follow Why stress suddenly feels different in your 40s The role of progesterone and ovulation in stress resilience Why many women feel tired but wired during perimenopause The difference between high cortisol, low cortisol and HPA-axis dysregulation The connection between cortisol and thyroid health How stress can affect digestion and gut function Simple lifestyle strategies that support healthy cortisol rhythms Links: Take my free perimenopause quiz: https://quiz.francescaliparoti.com/start-page Explore my Midlife Thrive membership: https://francescaliparoti.com/midlife-thrive-membership/ Work with me 121: https://francescaliparoti.com/services/ Connect with me on Instagram: https://www.instagram.com/perimenopause.with.francesca/ Support for the Empowered Perimenopause Podcast Your support in listening to these episodes means the absolute world to me and helps me make an impact with my work, which is why I’m here. I’d be so grateful if you could subscribe and share, and leave a review – 5 stars would be amazing and so helpful!

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This episode is 32 minutes long.

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This episode was published on March 9, 2026.

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