Episode 79 - Ghosts in the Machine | Basics of MDS & A Brief Look at AML

from Bloody Minded · host Bloody Minded Crew

Happy marrows are all alike; every unhappy marrow is unhappy in its own way. When haematopoiesis behaves itself, it’s frankly quite boring. When it goes rogue, it can get very creative. Join Cale, Bash and Nick as they attempt to walk through how this process goes off the rails, how MDS and AML are best understood and how dysplasia, cytopenias, blasts and clones all fit together.TIMESTAMPS0:55 - Our serious introduction to counterbalance last week 1:58 - Episode overview 2:50 - Introducing MDS 7:12 - Risk factors for MDS 8:53 - MDS progression 11:13 - Complications of MDS 13:10 - Leukaemic transformation 15:37 - MDS epidemiology 16:27 - Diagnosing MDS 21:19 - What is dysplasia? 26:44 - What we test on marrow 35:13 - Clonality assessment in MDS 42:29 - Caveats in diagnosing MDS 43:18 - MDS summary (finally) 44:09 - MDS treatment in brief 45:37 - Intro to AML 51:32 - Episode summary Support the showCheck out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

Episode metadata supplied by the publisher feed · Published Feb 24, 2026

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Episode 79 - Ghosts in the Machine | Basics of MDS & A Brief Look at AML

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