Episode 82: MCAS Explained: The Overlooked Condition Behind Chronic, Mysterious Symptoms

Episode 82 - Dr. Zac Spiritos breaks down what Mast Cell Activation Syndrome (MCAS) is and why it’s much more common than we think. Dr. Spiritos is a neurogastroenterologist known for connecting the dots between MCAS, POTS, hypermobility, gut dysfunction, and chronic unexplained symptoms. Together, we unpack why MCAS is so often missed, why it disproportionately affects women, and what it actually takes to begin feeling better. If you’ve ever felt sensitive to everything; smells, foods, heat, medications, stress, and struggled with symptoms that seem to jump from system to system, this episode is one you don’t want to miss. Our conversation explores why MCAS is notoriously difficult to diagnose, including the lack of reliable biomarkers and the way symptoms wax and wane, organ-hop, and defy traditional medical algorithms. We also discuss the cultural and structural reasons MCAS is dismissed, especially in women, and why many patients are incorrectly labeled as anxious or psychosomatic. Download & save Dr. Spiritos' MCAS handout here. Connect with Zac on Instagram at @drzacspiritos or on his website at everbettermedicine.health. Thanks for listening! Work with Uplift for Her and/or learn more about our offerings at upliftforher.com. New podcast episode every Tuesday! Connect with us on Instagram and YouTube at @upliftforher. If this episode spoke to you, please take a moment to rate, review, or share it with someone who needs to hear it. Your support helps us reach more women with compassionate, evidence-based guidance on their path to wellness.   Support our podcast by using any of the following links & Uplift For Her discount codes:  Amazon Storefront: https://www.amazon.com/shop/upliftforher Coconu: Use code “upliftforher” at checkout for 15% off at coconu.com Fullscript Supplement Shop: https://us.fullscript.com/welcome/mcracroft Just Ingredients: Use code “upliftforher” for 10% off at https://justingredients.us/UPLIFTFORHER LumeBox: Save $250 with our link. Click here to shop Needed: 20% of your first order with our link. Click here to shop Saalt Period Products: Use code “UPLIFTFORHER20” for 20% off. Click here to shop