Episode 85 - Wake Me Up! | Acute Promyelocytic Leukaemia (APML)

from Bloody Minded · host Bloody Minded Crew

What do arsenic, acne tablets and Jodi Picoult have in common? Why, it must be a deep dive with Nick, Bashar and Cale on acute promyelocytic leukaemia. From buzzwords to brain bleeds, the sweetest of translocations to the cruellest of coagulopathies... The yield is almost as high as the survival rates.TIMESTAMPS00:57 - Bloody Minded Poetry Jam & Jodi Picoult06:25 - APML Starts Here08:02 - APML - Where does it fit in AML?10:02 - Morphology & Flow12:12 - PML::RARA - t(15;17) and rare variants16:58 - Lab Summary17:50 - Clinical Presentation21:02 - APML Coagulopathy26:46 - Treatment and Risk Stratification33:53 - High Risk Aside36:58 - Differentiation Syndrome41:04 - Treatment SEs44:18 - Microgranular Variant47:00 - Summary and TakehomesSupport the showCheck out show notes, additional references and (sometimes) extra content at www.bloodyminded.com.au

Episode metadata supplied by the publisher feed · Published Apr 7, 2026

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Episode 85 - Wake Me Up! | Acute Promyelocytic Leukaemia (APML)

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