Episode 87 - Angioinvasive Fungal Infections from SF Derm Society 2024 Annual Meeting | The Future of Dermatology Podcast

Summary In this session from the 2024 SF Derm Society Annual Meeting, Dr. Lindy Fox discusses the critical topic of angioinvasive fungal infections, particularly in immunosuppressed patients. This truncated session covers the clinical presentation, diagnostic challenges, and emerging resistance patterns in fungal infections. Dr. Fox emphasizes the importance of recognizing the signs of invasive fungal infections and the need for broad coverage in treatment, especially given the rising rates of antifungal resistance. The episode concludes with key takeaways for dermatologists and a reminder of the podcast's educational purpose. Takeaways - Angioinvasive fungal infections are a significant concern for immunosuppressed patients. - Acute respiratory infections can increase the risk of invasive fungal infections. - Candida auris is a new resistant strain to be aware of. - Differentiating fungal organisms on H and E is unreliable; cultures are essential. - Antifungal resistance is on the rise, impacting treatment options. - Voreconazole does not treat mucor, leading to potential breakthrough infections. - L. prolificans is pan-resistant and often fatal. - Morphology is crucial in guiding the differential diagnosis of fungal infections. - Sweet syndrome can mimic other conditions histologically. - The podcast aims to educate and is not a substitute for medical advice. Chapters 00:00 - Introduction to the Future of Dermatology Podcast 00:53 - Understanding Angioinvasive Fungal Infections 03:49 - Clinical Pearls for Diagnosing Fungal Infections 08:02 - Diagnostic Considerations in Fungal Infections 10:06 - Therapeutic Considerations and Resistance Patterns