Epitalon: The wellness and longevity peptide! episode artwork

EPISODE · Jul 13, 2026 · 47 MIN

Epitalon: The wellness and longevity peptide!

from A Functional Approach with Dr. Jim Chialtas · host Jim Chialtas, DACM, L.Ac.

In this 137 episode, I showcase the peptide Epitalon. This amazing peptide has been shown to improve wellness and longevity by promoiting better sleep, improving immune function, improving endocrine function, improving immune function, and lowering cardiovascular and neurovascular risk. And... It works even better when combined with Thymulin-Zinc, which I discussed in my last episode!But don't just take my word for it! Here are some literature citations that are worth a read:References:Al-Dulaimi S, Thomas R, Matta S, Roberts T. Epitalon increases telomere length in human cell lines through telomerase upregulation or ALT activity. Biogerontology. 2025;26:178. doi:10.1007/s10522-025-10315-x.Anisimov VN, Arutjunyan AV, Khavinson VK. Effects of epithalamin on free-radical processes in humans and animals. Neuro Endocrinol Lett. 2001;22(1):9–18.Anisimov VN, Khavinson VK, Alimova IN, Semchenko AV, Yashin AI. Epithalon decelerates aging and suppresses breast adenocarcinoma development in transgenic HER-2/neu mice. Bull Exp Biol Med. 2002;134(2):187–190. doi:10.1023/A:1021104819170. PMID:12459848.Anisimov VN, Khavinson VK, Mikhailova EG, Yashin AI. Effect of epitalon on the incidence and age of spontaneous mammary carcinomas in female C3H mice. Bull Exp Biol Med. 2002;133(4):391–395. doi:10.1023/A:1017676104877.Anisimov VN, Khavinson VK, Popovich IG, Zabezhinski MA, Alimova IN, Rosenfeld SV, et al. Effect of epitalon on biomarkers of aging, lifespan, and spontaneous tumor incidence in female SHR mice. Biogerontology. 2003;4(4):193–202. doi:10.1023/A:1025114230714. PMID:14501183.Anisimov VN, Khavinson VK, Provinciali M, Alimova IN, Baturin DA, Popovich IG, et al. Inhibitory effect of epitalon on spontaneous mammary tumors in HER-2/neu transgenic mice. Int J Cancer. 2002;101(1):7–10. doi:10.1002/ijc.10570. PMID:12209581.Araj SK, Brzezik J, Mądra-Gackowska K, Szeleszczuk Ł. Overview of epitalon—highly bioactive pineal tetrapeptide with promising properties. Int J Mol Sci. 2025;26(6):2691. doi:10.3390/ijms26062691.Gatta M, Dovizio M, Milillo C, Ruggieri AG, Sallese M, Antonucci I, Trofimov A, Khavinson V, Trofimova S, Bruno A, Ballerini P. The antioxidant tetrapeptide Epitalon enhances delayed wound healing in an in vitro model of diabetic retinopathy. Stem Cell Rev Rep. 2025;21(6):1822–1834. doi:10.1007/s12015-025-10911-x.Goncharova ND, Vengerina AA, Shmalii AV, Khavinson VK. Peptide correction of age-related pineal dysfunction in monkeys. Adv Gerontol. 2003;12:121–127. [Russian]Goncharova ND, Vengerina AA, Khavinson VK, Lapin BA. Peptide correction of pancreatic hormonal dysfunction in aging monkeys. Bull Exp Biol Med. 2004;138(1):80–83. doi:10.1023/B:BEBM.0000046946.25425.f5.

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