Equine Asthma and Allergies.

This episode Nancy and Kate discuss 2 papers; the first is a paper that gives an update on the current understanding of Equine Asthma and also gives the future direction of research goals for this devastating disease. The 2nd paper tracks a molecule, IL-8, which has been found to signal equine allergic immune responses. This may be a component as to how horses and humans develop allergic responses. Both papers are referenced below. Couetil, L., Cardwell, J. M., Leguillette, R., Mazan, M., Richard, E., Bienzle, D., Bullone, M., Gerber, V., Ivester, K., Lavoie, J. P., Martin, J., Moran, G., Niedźwiedź, A., Pusterla, N., & Swiderski, C. (2020). Equine Asthma: Current Understanding and Future Directions. Frontiers in veterinary science, 7, 450. https://doi.org/10.3389/fvets.2020.00450 Elisabeth M. Larson, Susanna Babasyan, Bettina Wagner; IgE-Binding Monocytes Have an Enhanced Ability to Produce IL-8 (CXCL8) in Animals with Naturally Occurring Allergy. J Immunol 15 May 2021; 206 (10): 2312–2321.  https://doi.org/10.4049/jimmunol.2001354