Skip to content
Essentials: Psychedelics for Treating Mental Disorders | Dr. Matthew Johnson episode artwork

Jul 24, 2025 39 min

Essentials: Psychedelics for Treating Mental Disorders | Dr. Matthew Johnson

from Huberman Lab Hosted by Scicomm Media

In this Huberman Lab Essentials episode, my guest is Dr. Matthew Johnson, PhD, a senior researcher for the Center of Excellence for Psilocybin Research and Treatment at Sheppard Pratt’s Institute for Advanced Diagnostics and Therapeutics. We explore the science and therapeutic potential of psychedelic medicine, including psilocybin, MDMA and LSD. We discuss how these substances can profoundly alter perception and self-identity, providing long-lasting relief from depression, addiction and trauma when used in controlled clinical settings. We also discuss microdosing and emerging research on psychedelics’ potential to support recovery from neurological injuries. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman David: https://davidprotein.com/huberman BetterHelp: https://betterhelp.com/huberman Timestamps 00:00:00 Matthew Johnson; Psychedelics 00:01:44 Different Classes of Psychedelics 00:04:33 Psychedelics & Altering Models 00:06:18 Sponsor: David 00:07:33 LSD, Psylocibin & Serotonin 00:09:55 Psychedelic Clinical Trials 00:13:40 Therapy, Trust, Psychedelics 00:16:47 Letting Go & Psychedelic Experience, Self-Representation, Lasting Changes 00:22:31 Sponsors: AG1 & BetterHelp 00:25:26 MDMA, Dopamine & Serotonin; Bad Trips & Transcendental Experience 00:28:49 Dangers of Psychedelics 00:31:11 Microdosing Psychedelics, Antidepressant 00:35:27 Head Injuries, Psychedelics, Depression 00:38:29 Acknowledgements Disclaimer & Disclosures

Episode details come from the podcast's RSS feed.

Embed this episode

Ready to play

Essentials: Psychedelics for Treating Mental Disorders | Dr. Matthew Johnson

0:00 39:09

No transcript yet.

Requests help us decide what to transcribe next.

Frequently asked questions

How long is this episode of Huberman Lab?

This episode is 39 minutes long.

When was this Huberman Lab episode published?

This episode was published on July 24, 2025.

Can I download this Huberman Lab episode?

Yes. Use the download control on the episode player to save the publisher-provided media file.