Ethereum's Layer 1 Lacks a Perp DEX. Synthetix Intends to Change That - Ep. 926 episode artwork

EPISODE · Oct 17, 2025 · 55 MIN

Ethereum's Layer 1 Lacks a Perp DEX. Synthetix Intends to Change That - Ep. 926

from Unchained · host Laura Shin

Kain Warwick, founder of Synthetix and Infinex, is returning to Ethereum Layer 1 with a bold new experiment: a perpetuals DEX built directly on mainnet. In this episode, he joins Laura to explain why Synthetix is taking this contrarian step, how its hybrid “optimistic order book” can run efficiently on Ethereum’s slower block times, and why he believes the future of trading will move fully on-chain. Warwick also discusses the tradeoffs behind using USDT, what it will take to match centralized exchange performance, and his “super app” vision for how DeFi platforms could finally outcompete CEXs. Thank you to our sponsor, ⁠Binance⁠! Guest: Kain Warwick, Founder of Infinex and Synthetix Links: The Superapp Thesis by Kain Warwick Blockwork’s Dan Smith on Spreads for ETH-USD Timestamps: 🔥 0:00 Introduction and ads: Binance ⚙️ 0:56 Why Synthetix is launching a perps DEX directly on Ethereum mainnet ⏳ 5:18 How a perpetuals exchange can even work on slow Ethereum block times 🔍 10:34 How transparency will differ from other onchain trading venues 🏗️ 13:53 Why Kain believes being on Ethereum mainnet still matters 🧱 17:00 The challenges of operating on L1—margin posting, gas costs, and more ⚔️ 21:43 How Synthetix plans to compete in an overcrowded perps DEX landscape 💣 24:33 How liquidations on an Ethereum perp DEX would play out during a Black Friday-like crash 🕵️‍♂️ 29:32 How traders could maintain privacy while staying fully decentralized 🌐 31:57 Why a perps DEX on mainnet could reshape Ethereum DeFi 💵 34:25 Why Synthetix is using USDT—despite its centralization risks 🏦 37:28 Which premium assets will serve as collateral 📱 39:36 Inside Kain’s “super app” vision for DeFi’s next evolution 🏁 50:31 Why Kain is fired up about Synthetix’s upcoming trading competition Learn more about your ad choices. Visit megaphone.fm/adchoices

Kain Warwick, founder of Synthetix and Infinex, is returning to Ethereum Layer 1 with a bold new experiment: a perpetuals DEX built directly on mainnet. In this episode, he joins Laura to explain why Synthetix is taking this contrarian step, how its hybrid “optimistic order book” can run efficiently on Ethereum’s slower block times, and why he believes the future of trading will move fully on-chain. Warwick also discusses the tradeoffs behind using USDT, what it will take to match centralized exchange performance, and his “super app” vision for how DeFi platforms could finally outcompete CEXs. Thank you to our sponsor, ⁠Binance⁠! Guest: Kain Warwick, Founder of Infinex and Synthetix Links: The Superapp Thesis by Kain Warwick Blockwork’s Dan Smith on Spreads for ETH-USD Timestamps: 🔥 0:00 Introduction and ads: Binance ⚙️ 0:56 Why Synthetix is launching a perps DEX directly on Ethereum mainnet ⏳ 5:18 How a perpetuals exchange can even work on slow Ethereum block times 🔍 10:34 How transparency will differ from other onchain trading venues 🏗️ 13:53 Why Kain believes being on Ethereum mainnet still matters 🧱 17:00 The challenges of operating on L1—margin posting, gas costs, and more ⚔️ 21:43 How Synthetix plans to compete in an overcrowded perps DEX landscape 💣 24:33 How liquidations on an Ethereum perp DEX would play out during a Black Friday-like crash 🕵️‍♂️ 29:32 How traders could maintain privacy while staying fully decentralized 🌐 31:57 Why a perps DEX on mainnet could reshape Ethereum DeFi 💵 34:25 Why Synthetix is using USDT—despite its centralization risks 🏦 37:28 Which premium assets will serve as collateral 📱 39:36 Inside Kain’s “super app” vision for DeFi’s next evolution 🏁 50:31 Why Kain is fired up about Synthetix’s upcoming trading competition Learn more about your ad choices. Visit megaphone.fm/adchoices

NOW PLAYING

Ethereum's Layer 1 Lacks a Perp DEX. Synthetix Intends to Change That - Ep. 926

0:00 55:46

No transcript for this episode yet

We transcribe on demand. Request one and we'll notify you when it's ready — usually under 10 minutes.

Unshamed & Unchained: Carving Space For Self-Healing & Habit Transformation Danny Poelman Welcome to "Unshamed & Unchained: Carving Space For Self-Healing & Habit Transformation", the podcast where we break the chains of shame and societal expectations to create a safe space for self-healing, habit transformation, and personal growth. Hosted by a seasoned life coach, Danny Poelman DDS, with years of hands-on experience, this podcast is your guide to reclaiming your voice, embracing your story, and living life on your terms.In each episode, we dive deep into the topics that matter most to you—whether it's:-breaking free from unwanted habits like pornography-excessive people-pleasing-healing from past trauma-recovering from narcissistic abuse or religious/relational trauma-anxiety/depression-money mindset blocks-overcoming limiting beliefsWe’re not afraid to talk about the things that are often considered taboo, because we believe that through honest, unfiltered conversations, real transformation happens.You’ll hear real INDIÉ LÖVE, FÖR RÉAL EUGKEN Btw INDIE LOVE, FOR REAL is a heartfelt, genre-blending track that captures the raw, unfiltered essence of independent love—pure, intentional, and unchained by mainstream expectations. With mellow instrumentals and emotionally charged vocals, the song paints a vivid picture of love that’s authentic and uncompromising.Songwriter: Eugene MgonyaProducer: Rosco Beats Interchain.FM Chjango Unchained Interchain.FM is the Cosmos Radio Station which shines a light on the protocols that solve the hardest problems in Web3. It's a technical podcast that uncovers the vibrant world of bleeding edge technology built in the pursuit of anti-censorship, freedom, and preserving the privacy of the sovereign individual. Become an Interchain.FM🥩 staker on Osmosis, Comdex, and Umee! The Unchained Mind Alex Rudnicka Welcome to The Unchained Mind, where we dive into the power of mindset for entrepreneurs. Join us as we explore the art of creating your own reality through the limitless potential of your mind. Unshackle yourself from limiting beliefs and unlock the keys to entrepreneurial success with simple mindset strategies that help you create your reality using the power of your mind.

Frequently Asked Questions

How long is this episode of Unchained?

This episode is 55 minutes long.

When was this Unchained episode published?

This episode was published on October 17, 2025.

What is this episode about?

Kain Warwick, founder of Synthetix and Infinex, is returning to Ethereum Layer 1 with a bold new experiment: a perpetuals DEX built directly on mainnet. In this episode, he joins Laura to explain why Synthetix is taking this contrarian step, how its...

Can I download this Unchained episode?

Yes, you can download this episode by clicking the download button on the episode player, or subscribe to the podcast in your preferred podcast app for automatic downloads.
URL copied to clipboard!