Exclusive Look at CL1: One-on-One with Cortical Labs’ Chief Scientist episode artwork

EPISODE · Apr 16, 2025 · 42 MIN

Exclusive Look at CL1: One-on-One with Cortical Labs’ Chief Scientist

from Spatial Web AI Podcast · host Denise Holt

In this exclusive podcast interview, Denise Holt sits down with Brett Kagan, Chief Scientist at Cortical Labs, for an in-depth exploration into their groundbreaking synthetic biological intelligence (SBI) technology. Brett reveals the science behind their revolutionary CL1 system—the first commercial biological computer fusing live human neurons with silicon computing. We discuss how their DishBrain experiment validated Dr. Karl Friston's Free Energy Principle, the extraordinary energy efficiency of biological intelligence, and the significant implications for industries like drug discovery, personalized medicine, and robotics. Don't miss this insightful conversation, rich with first-hand stories and detailed explanations from the forefront of neuroscience and AI innovation. #CorticalLabs #CL1 #ActiveInferenceAIKey Topics:·  The CL1 System: How Cortical Labs successfully merged live human neurons with silicon chips to create the first synthetic biological intelligence computing system.·  DishBrain Experiment: Insights into the groundbreaking experiment validating Dr. Karl Friston's Free Energy Principle through neuron-based Pong gameplay.·  Energy Efficiency of Biological Intelligence: Understanding how biological neurons provide vastly superior energy efficiency compared to traditional AI systems.·  Ethical Implications: Brett Kagan's candid discussion on the responsible use of human neurons in research and their potential to reduce animal testing.·  Real-world Applications: The transformative impact of synthetic biological intelligence on drug discovery, personalized medicine, and robotics.Guest:Brett Kagan, Chief Scientific Officer at Cortical LabsHost: Denise Holt, CEO and Founder, AIX Global MediaHuge thank you to Brettfor being on our show! Discover more about Cortical Labs: https://corticallabs.com Looking for education resources and courses on Active Inference, the Free Energy Principle, and Spatial Web Technologies? Visit Learning Lab Central to find others around the world who are just as excited for this new shift in AI and computing:https://learninglab.emmersionpublishing.com #CorticalLabs #CL1 #FreeEnergyPrinciple#ActiveInferenceAi

In this exclusive podcast interview, Denise Holt sits down with Brett Kagan, Chief Scientist at Cortical Labs, for an in-depth exploration into their groundbreaking synthetic biological intelligence (SBI) technology. Brett reveals the science behind their revolutionary CL1 system—the first commercial biological computer fusing live human neurons with silicon computing. We discuss how their DishBrain experiment validated Dr. Karl Friston's Free Energy Principle, the extraordinary energy efficiency of biological intelligence, and the significant implications for industries like drug discovery, personalized medicine, and robotics. Don't miss this insightful conversation, rich with first-hand stories and detailed explanations from the forefront of neuroscience and AI innovation. #CorticalLabs #CL1 #ActiveInferenceAIKey Topics:·  The CL1 System: How Cortical Labs successfully merged live human neurons with silicon chips to create the first synthetic biological intelligence computing system.·  DishBrain Experiment: Insights into the groundbreaking experiment validating Dr. Karl Friston's Free Energy Principle through neuron-based Pong gameplay.·  Energy Efficiency of Biological Intelligence: Understanding how biological neurons provide vastly superior energy efficiency compared to traditional AI systems.·  Ethical Implications: Brett Kagan's candid discussion on the responsible use of human neurons in research and their potential to reduce animal testing.·  Real-world Applications: The transformative impact of synthetic biological intelligence on drug discovery, personalized medicine, and robotics.Guest:Brett Kagan, Chief Scientific Officer at Cortical LabsHost: Denise Holt, CEO and Founder, AIX Global MediaHuge thank you to Brettfor being on our show! Discover more about Cortical Labs: https://corticallabs.com Looking for education resources and courses on Active Inference, the Free Energy Principle, and Spatial Web Technologies? Visit Learning Lab Central to find others around the world who are just as excited for this new shift in AI and computing:https://learninglab.emmersionpublishing.com #CorticalLabs #CL1 #FreeEnergyPrinciple#ActiveInferenceAi

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Exclusive Look at CL1: One-on-One with Cortical Labs’ Chief Scientist

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This episode was published on April 16, 2025.

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In this exclusive podcast interview, Denise Holt sits down with Brett Kagan, Chief Scientist at Cortical Labs, for an in-depth exploration into their groundbreaking synthetic biological intelligence (SBI) technology. Brett reveals the science behind...

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