Fact Sheet: President Donald J. Trump Launches TrumpRx.gov to Bring Lower Drug Prices to American Patients

The Trump Administration has officially launched TrumpRx.gov, a new digital platform designed to provide Americans with massive discounts on high-priced prescription medications. The initiative is based on the “Most-Favored-Nation” (MFN) pricing model, which ensures that U.S. patients pay prices in line with the lowest rates offered in other developed countries.Direct Savings: Patients with valid prescriptions can access discounts via user-friendly coupons (printed or mobile) or through direct manufacturer channels integrated into the site.Initial Manufacturers: The launch features medications from five major companies: AstraZeneca, Eli Lilly, EMD Serono, Novo Nordisk, and Pfizer. More companies are expected to be added as they finalize MFN deals.Scale: The site currently offers significant price reductions on 40 of the most popular and expensive branded medicines in the U.S.The administration highlighted several dramatic price cuts for chronic and high-cost conditions:Diabetes and Weight Loss (GLP-1s):Ozempic and Wegovy monthly prices will drop from over Zepbound prices will drop to an average of $346.Fertility Treatments: Patients stands to save an average of $2,000 per cycle. For example, Cetrotide will drop from Respiratory and Chronic Care:Bevespi Aerosphere (COPD) inhalers will drop from Insulin Lispro will be available for as low as $25 per month.Duavee (Hot Flashes/Osteoporosis) will drop from The launch of TrumpRx.gov is the culmination of a multi-step "America First" healthcare strategy:Executive Action: Following a May 2025 Executive Order, the administration has secured 16 MFN deals with pharmaceutical giants.Global Fairness: In December 2025, the administration negotiated an agreement with the United Kingdom to raise their net drug prices by 25%, ensuring foreign allies "pay their fair share" for innovation rather than being subsidized by American patients.Legislation: President Trump is currently calling on Congress to codify these MFN savings into law as part of “The Great Healthcare Plan.”Conclusion:By launching TrumpRx.gov, the Trump Administration aims to fulfill a primary campaign promise: ending the era of Americans paying the highest drug prices in the world. The initiative uses market leverage and international negotiation to provide immediate financial relief to millions of patients.Key Features of TrumpRx.govMajor Price ReductionsStrategic Context and Negotiations