Fat Grafting — Biology, Harvest, Processing, Injection Strategy, and Regenerative Applications

This episode reviews the core principles of autologous fat grafting in plastic surgery, focusing on fat biology, graft survival, harvest, processing, and injection technique.Topics include white adipose tissue, mature adipocytes, stromal vascular fraction, adipose-derived stem cells, ischemia tolerance, the IIR timeline of imbibition, inosculation, and revascularization, and the 3 mm aliquot rule for graft survival. The episode also covers donor-site selection, tumescent timing, Coleman harvest, SAFE lipo, centrifugation, Telfa rolling, facial fat grafting, tear trough and periorbital safety, breast fat grafting, radiation fibrosis, and gluteal fat grafting safety. Part of Dr. Lara’s Plastic Surgery Compendium — a high-yield audio reference for plastic surgery trainees and surgeons.DisclaimerThis podcast is intended for educational purposes only and is designed for medical students, residents, fellows, and practicing healthcare professionals. It is not intended to provide medical advice, diagnosis, or treatment for any individual patient. The content presented reflects general surgical principles and should not be used as a substitute for formal medical training, clinical judgment, or consultation with qualified healthcare professionals. Listening to this podcast does not establish a physician–patient relationship.SEO / Topic Keywordsfat grafting, autologous fat grafting, fat transfer, facial fat grafting, breast fat grafting, gluteal fat grafting, BBL safety, adipose-derived stem cells, stromal vascular fraction, SVF, mature adipocytes, graft survival, imbibition, inosculation, revascularization, 3 mm rule, Coleman technique, SAFE lipo, fat harvest, tumescent fluid, centrifugation, Telfa rolling, fat processing, tear trough fat grafting, periorbital fat grafting, fat embolism, radiation fibrosis, regenerative fat grafting