FDA Approval of Telisotuzumab (Teliso-V) in c-MET Overexpression - LUMINOSITY trial episode artwork

EPISODE · Jun 27, 2025 · 11 MIN

FDA Approval of Telisotuzumab (Teliso-V) in c-MET Overexpression - LUMINOSITY trial

from Oncology Brothers: Practice-Changing Cancer Discussions · host Oncology Brothers

Welcome to another episode of the Oncology Brothers podcast! In this episode, Drs. Rahul and Rohit Gosain are joined by Dr. Ross Camidge, a leading thoracic medical oncologist from the University of Colorado, to discuss the recent approval of telisotuzumab-vedotin (Teliso-V) for metastatic non-small cell lung cancer (NSCLC) with C-met overexpression, based on the LUMINOSITY trial.Join us as we explore:• The mechanism of action of telisotuzumab and its role as an antibody-drug conjugate.• The prevalence of C-met overexpression in NSCLC and its implications for testing and treatment.• Key findings from the Luminosity trial, including response rates and study design.• The importance of C-met testing in clinical practice.• Management of side effects associated with telisotuzumab, particularly peripheral neuropathy.Follow us on social media:•⁠ ⁠X/Twitter: https://twitter.com/oncbrothers•⁠ ⁠Instagram: https://www.instagram.com/oncbrothers•⁠ Website: https://oncbrothers.com/This episode is packed with valuable insights for oncologists and healthcare professionals navigating the evolving landscape of lung cancer treatment. Don't miss out on this informative discussion!

Welcome to another episode of the Oncology Brothers podcast! In this episode, Drs. Rahul and Rohit Gosain are joined by Dr. Ross Camidge, a leading thoracic medical oncologist from the University of Colorado, to discuss the recent approval of telisotuzumab-vedotin (Teliso-V) for metastatic non-small cell lung cancer (NSCLC) with C-met overexpression, based on the LUMINOSITY trial.Join us as we explore:• The mechanism of action of telisotuzumab and its role as an antibody-drug conjugate.• The prevalence of C-met overexpression in NSCLC and its implications for testing and treatment.• Key findings from the Luminosity trial, including response rates and study design.• The importance of C-met testing in clinical practice.• Management of side effects associated with telisotuzumab, particularly peripheral neuropathy.Follow us on social media:•⁠ ⁠X/Twitter: https://twitter.com/oncbrothers•⁠ ⁠Instagram: https://www.instagram.com/oncbrothers•⁠ Website: https://oncbrothers.com/This episode is packed with valuable insights for oncologists and healthcare professionals navigating the evolving landscape of lung cancer treatment. Don't miss out on this informative discussion!

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FDA Approval of Telisotuzumab (Teliso-V) in c-MET Overexpression - LUMINOSITY trial

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This episode is 11 minutes long.

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This episode was published on June 27, 2025.

What is this episode about?

Welcome to another episode of the Oncology Brothers podcast! In this episode, Drs. Rahul and Rohit Gosain are joined by Dr. Ross Camidge, a leading thoracic medical oncologist from the University of Colorado, to discuss the recent approval of...

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