FDA Clears Ezplaz. Here’s What EMS Needs to Know.

FDA has cleared Ezplaz, a shelf‑stable freeze‑dried plasma product, opening new possibilities for prehospital transfusion. In this episode Dr. Matt Levy and Dr. Randi Schaefer walk through the history, physiology, and practical realities of dried plasma: why it can stabilize bleeding patients, how it’s reconstituted, and where it fits alongside whole blood and component therapy. They emphasize that this is not a plug‑and‑go item—dried plasma remains a regulated blood product requiring medical director oversight, temperature management, documentation, and stewardship. Listen for implementation tips, regulatory limitations (approved for adults and currently intended where liquid plasma isn’t available), cost and distribution considerations, and how to prepare your system and crews.   NOTE: The military was officially approved to use FDP in 2018. Efforts started earlier.