February: Pharamcogenetic profiling in children with medical complexity

Children with medical complexity typically require multiple medications throughout the course of their treatment. These individuals also increasingly undergo genome-wide testing early in life as a diagnostic test. Since many medications prescribed to children have established gene-drug interactions, could this genetic data be repurposed to aid precision prescribing in this priority pediatric population? In today's Pediapod, we meet Early Career Investigator, Gregory Costain, a physician scientist at The Hospital for Sick Children in Toronto, Canada who recently published a retrospective study which looked at this question. Read the full study here: https://www.nature.com/articles/s41390-022-02313-3