Fibrates (Fenofibrate & Gemfibrozil) for TG: Pharmacology Made Easy

Learn fibrates (fibric acid derivatives)—fenofibrate and gemfibrozil—common triglyceride-lowering drugs for hypertriglyceridemia. In this lecture from This is Why, Dr. Busti will break down how fibrates (fenofibrate and gemfibrozil) work, when to use them, and the safety pearls you need for the patient with high triglycerides, which can lead to pancreatitis.You’ll learn how to:- Mechanism: PPAR-α activation → ↓ triglycerides (TG), ↓ VLDL, ↑ HDL- Fenofibrate vs gemfibrozil: key differences that matter for practice questions- Indications: managing high triglycerides (including reducing pancreatitis risk in severe TG)- Adverse effects & monitoring: myopathy risk, LFTs, gallstones, and what to watch for- Drug interactions: especially with statins (testable!)The goal = make medical education easy and clinically relevant.👉 Access bonus materials and downloads from this episode at: https://www.thisiswhy.health/topics/fibrates-fenofibrate-gemfibrozil-hypertriglyceridemia-triglycerides-pharmacology👉 Get more with a free membership at https://www.thisiswhy.health/- Access free downloads from our videos - Access deep dive content from Dr. Busti- Organize content via playlists & collections- Join live Q&A- Receive member newsletters- Coupons & discounts for exam prep resources👍 If this helped you, please like, subscribe, and share it with a classmate or colleague. That will help this new channel continue producing free, high-yield medical education content.🔔 Don’t forget to turn on notifications so you don’t miss upcoming lectures in pharmacology, medical rounds, and more!#fibrates #fenofibrate #gemfibrozil #hypertriglyceridemia #bustiDisclaimer:This content is for educational purposes only and is not medical advice. It does not replace individualized evaluation, diagnosis, or treatment. Always seek the advice of a qualified health provider with questions about a medical condition and never delay care because of educational content.