Figuring out how THC works in the brain with Dr. Allyn Howlett episode artwork

EPISODE · May 2, 2025 · 1H 3M

Figuring out how THC works in the brain with Dr. Allyn Howlett

from BIOACTIVE · host Riley D. Kirk, Ph.D.

In this episode of the Bioactive Podcast, Dr. Allyn Howlett—renowned neuroscientist and pioneer in cannabinoid research—shares her groundbreaking journey into the study of cannabis and the discovery of the CB1 receptor. Originally focused on neuronal hormones, Dr. Howlett recounts how her curiosity led to one of the most pivotal findings in medical cannabis science: the identification of the brain’s first cannabinoid receptor. She dives into the mechanisms of THC, the function of cannabinoid receptors in the brain and body, and the discovery of the endocannabinoid system. The conversation explores the historical development of cannabinoid research, the barriers posed by the pharmaceutical industry, and the evolving relationship between academia and drug development. Dr. Howlett also discusses the future of cannabinoid science—including targeted therapies, pain relief, and the medical potential of cannabis compounds. This episode offers an essential look at the scientific foundation behind cannabis medicine and its impact on legalization, healthcare, and public perception. 🔬 Keywords: CB1 receptor, endocannabinoid system, THC, cannabis research, Dr. Allyn Howlett, cannabinoid receptors, medical cannabis, neuroscience, cannabis and pain relief, cannabis legalization, targeted cannabinoid therapies. Follow Dr.Howlett's research: https://school.wakehealth.edu/faculty/h/allyn-howlett Preorder my book Reefer Wellness! ⁠https://www.amazon.com/Reefer-Wellness-Understanding-Cannabis-Medicine/dp/0593847156⁠ ✨ Want Exclusive Content? Join the Bioactive Patreon community for as little as $1/month to ask guests your burning questions, access exclusive content, and connect with Dr. Kirk one-on-one.⁠ www.Patreon.com/Cannabichem⁠ 🔔 Don’t forget to like, subscribe, and hit the notification bell for more expert insights into cannabis science, plant biology, and more! Keep up with Dr. Riley Kirk: https://www.bioactivepodcast.com/ https://www.youtube.com/@cannabichem https://instagram.com/cannabichem ⁠https://www.appliedpharmacognosy.org/⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode of the Bioactive Podcast, Dr. Allyn Howlett—renowned neuroscientist and pioneer in cannabinoid research—shares her groundbreaking journey into the study of cannabis and the discovery of the CB1 receptor. Originally focused on neuronal hormones, Dr. Howlett recounts how her curiosity led to one of the most pivotal findings in medical cannabis science: the identification of the brain’s first cannabinoid receptor. She dives into the mechanisms of THC, the function of cannabinoid receptors in the brain and body, and the discovery of the endocannabinoid system. The conversation explores the historical development of cannabinoid research, the barriers posed by the pharmaceutical industry, and the evolving relationship between academia and drug development. Dr. Howlett also discusses the future of cannabinoid science—including targeted therapies, pain relief, and the medical potential of cannabis compounds. This episode offers an essential look at the scientific foundation behind cannabis medicine and its impact on legalization, healthcare, and public perception. 🔬 Keywords: CB1 receptor, endocannabinoid system, THC, cannabis research, Dr. Allyn Howlett, cannabinoid receptors, medical cannabis, neuroscience, cannabis and pain relief, cannabis legalization, targeted cannabinoid therapies. Follow Dr.Howlett's research: https://school.wakehealth.edu/faculty/h/allyn-howlett Preorder my book Reefer Wellness! ⁠https://www.amazon.com/Reefer-Wellness-Understanding-Cannabis-Medicine/dp/0593847156⁠ ✨ Want Exclusive Content? Join the Bioactive Patreon community for as little as $1/month to ask guests your burning questions, access exclusive content, and connect with Dr. Kirk one-on-one.⁠ www.Patreon.com/Cannabichem⁠ 🔔 Don’t forget to like, subscribe, and hit the notification bell for more expert insights into cannabis science, plant biology, and more! Keep up with Dr. Riley Kirk: https://www.bioactivepodcast.com/ https://www.youtube.com/@cannabichem https://instagram.com/cannabichem ⁠https://www.appliedpharmacognosy.org/⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices

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Figuring out how THC works in the brain with Dr. Allyn Howlett

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Bioactive Live Q&A Mark Ashworth "Bioactive Live Q&A" is a podcast dedicated to exploring the world of healthy soils and how it relates to Regenerative Agriculture, Bioactive Enclosures, No-Till Cannabis Farming, Permaculture and more!Join us as we dive deep into the benefits of creating a thriving ecosystem within your own home or farm, using organic and sustainable methods. Our expert guests will answer your burning questions and provide valuable insights to help you create a healthier and more vibrant environment for your plants and animals. Tune in to "Bioactive Live Q&A" for all the latest tips, tricks, and advice on bioactive enclosures, regenerative processes and natural farming [email protected] From Sea to Science: Natural Health with Aroma New Zealand Danny From Sea to Science explores how New Zealand’s pristine marine resources and cutting-edge research are transforming health for people and pets. From the nutrient-rich green-lipped mussel to advanced bioactive testing at the Zealife Institute, each episode uncovers the stories, science, and sustainability behind some of the world’s most powerful natural health solutions. Prof Johnathan Napier - Fish oils and seeds for healthy foods Omega-3 fatty acids - obtained from fish oils - are vital for human health, but there is no sustainable production system in place for them. Fisheries are not run sustainably, and the marine environment is suffering from pollution which can accumulate in fish. Unfortunately, popular plant oils such as flax and linseed lack the bioactive omega-3 fatty acids that humans need. We need an alternative and sustainable source of these important compounds to tackle the health issues of the 21st century.Prof Johnathan Napier works at Rothamsted Research in Hertfordshire, a government-funded insitution and the oldest agricultural research station in the world. He and his group have been working to engineer transgenic plants to accumulate omega-3 fatty acids. Dr Finian Leeper – From Bioactive Natural Products to Cancer Imaging Video of Dr Finian Leeper outlining his research to prospective Ph.D. students at the Department of Chemistry during Graduate Open Day on Friday 20th October 2017

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This episode was published on May 2, 2025.

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In this episode of the Bioactive Podcast, Dr. Allyn Howlett—renowned neuroscientist and pioneer in cannabinoid research—shares her groundbreaking journey into the study of cannabis and the discovery of the CB1 receptor. Originally focused on...

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