Fixing pre-launch commercial ops mistakes

What this episode covers

Operating model. Launch readiness. Data. Execution. Get these wrong, and even the most promising therapy can stall. Get them right, and you get product to patient — and that’s what drives Lori Nemyier every day. In this inaugural episode of the Space Life Sciences Podcast, Marc Iskowitz sits down with Lori to unpack a critical question for emerging biotechs: Why do so many companies struggle to execute at launch, and how can they get it right the first time? Drawing on more than two decades of experience across specialty pharma and startup environments, Lori shares what she’s learned from stepping into companies at pivotal inflection points — often tasked with building or rebuilding commercial operations from the ground up. (00:00) Introduction(01:37) What draws Lori to early-stage biotech startups (02:42) Lori's "Welcome to Biopharma" moment (04:24) Challenges of launching in cell and gene therapy (06:37) Data acquisition strategy before a drug launch (08:39) The #1 tip for winning at launch (10:38) Real example: Getting tech and data to work in sync (12:38) Where AI is effective in life sciences (14:49) The biggest AI opportunities in biopharma (16:35) Final advice for commercial leaders

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