Fixing the $100B Fluid Overload Crisis in Heart & Kidney Disease | Ryan Marthaler - Vice President of Product Marketing and Business Development, Nuwellis episode artwork

EPISODE · May 21, 2026 · 33 MIN

Fixing the $100B Fluid Overload Crisis in Heart & Kidney Disease | Ryan Marthaler - Vice President of Product Marketing and Business Development, Nuwellis

from Progress, Potential, and Possibilities Podcast / Show · host Ira Pastor / Ryan Marthaler

Send us Fan MailOne of the biggest drivers of hospital admissions isn’t what most people think - it’s fluid. Not infection, not surgery…fluid overload. And when the body stops responding to diuretics, medicine runs into a wall.Today we’re exploring one of the most challenging and underappreciated frontiers in hospital medicine: fluid overload and the cardiorenal continuum - where heart failure and kidney dysfunction intersect in ways that dramatically affect outcomes, costs, and quality of life.Our guest is Ryan Marthaler, Vice President of Product Marketing and Business Development at Nuwellis, Inc. ( https://nuwellis.com/ ), a medical technology company focused on integrated fluid management solutions for both adult and pediatric patients.Ryan brings a two-decade career spanning Medtronic, St. Jude Medical, and digital health innovation - working at the intersection of clinical evidence, commercial strategy, and product development. At Nuwellis, he has helped drive a strategic shift toward earlier intervention in fluid management and stronger evidence-based commercialization.We’ll be discussing the company’s core therapy platform, including the Aquadex SmartFlow System, a controlled ultrafiltration system designed to remove excess fluid in patients with fluid overload who are unresponsive to diuretics.Beyond the technology, this conversation is really about a bigger question:How do we better manage fluid balance across the heart-kidney axis - and what happens when we intervene earlier, more precisely, and more consistently?#HeartFailure #CardiorenalSyndrome #FluidOverload #HealthcareInnovation #MedicalDevices #CriticalCare #Nephrology #Cardiology #HospitalMedicine #MedTech #Ultrafiltration #KidneyDisease #ICU #HealthTech #HealthcareEconomics #MedicalInnovationSupport the show

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Send us Fan Mail One of the biggest drivers of hospital admissions isn’t what most people think - it’s fluid. Not infection, not surgery…fluid overload. And when the body stops responding to diuretics, medicine runs into a wall. Today we’re exploring one of the most challenging and underappreciated frontiers in hospital medicine: fluid overload and the cardiorenal continuum - where heart failure and kidney dysfunction intersect in ways that dramatically affect outcomes, costs, and quality of...

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Fixing the $100B Fluid Overload Crisis in Heart & Kidney Disease | Ryan Marthaler - Vice President of Product Marketing and Business Development, Nuwellis

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