Freely Filtered 005 IgA Nephropathy

Joel Topf Jennie Lin Matt Sparks Swapnil Hiremath Show Notes: IgA Nephropathy Score Levi Strauss: https://www.biography.com/fashion-designer/levi-strauss Levey MDRD study: https://www.ncbi.nlm.nih.gov/pubmed/10075613 ADPKD Total Kidney Volume: https://www.nejm.org/doi/10.1056/NEJMoa054341 Halt PKD: https://www.nejm.org/doi/full/10.1056/nejmoa1402685 Tempo 3:4 Trial: https://www.nejm.org/doi/full/10.1056/NEJMoa1205511 Description description of IgA nephropathy by Berger and Hiunglais: https://www.ncbi.nlm.nih.gov/pubmed/4180586 The reprint in JASN in 2000 with commentary as part of the Milestones in Nephrology series: https://jasn.asnjournals.org/content/jnephrol/11/10/1957.full.pdf JASN supplies an English translation from the original French. Nice reference from JASN backing up Matt’s assertion that preeclampsia and not IgA nephropathy is the most common glomerular disease in the world: https://jasn.asnjournals.org/content/18/8/2281 Description of the Singapore Army screening recruits from the Oxford Textbook of Clinical Nephrology: https://books.google.com/books?id=fVItBQAAQBAJ&lpg=PA485&ots=JRoOnUnleT&dq=singapore%20kidney%20biopsy%20army&pg=PA485#v=onepage&q&f=false Description of the Japanese glomerulonephritis screening program: https://cjasn.asnjournals.org/content/2/6/1360 Swapnil’s studies on autopsy studies: Finland: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC501386/ Japan: https://www.ncbi.nlm.nih.gov/pubmed/12753320/ Nephrology Secrets, either one of the best or the best nephrology textbooks ever: https://www.amazon.com/Nephrology-Secrets-Book-Edgar-Lerma-ebook/dp/B079TSYNQW/ref=sr_1_1 TESTING Trial on NephJC: http://www.nephjc.com/news/2017/8/28/testing Stop-Iga Trial on NephJC: http://www.nephjc.com/iga-nephropathy Testing Trial two: Therapeutic Evaluation of Steroids in IgA Nephropathy Global Study Low Dose Study: https://clinicaltrials.gov/ct2/show/NCT01560052 MEST Score versus MEST-C in NephJC: http://www.nephjc.com/news/2016/10/16/do-crescents-matter-for-iga-nephropathy Nice discussion of the statistical tests during the Tweet Chat by people who know their stats (I.e. not Joel): https://twitter.com/NephJC/status/1133546750814367746 Tweet-length description of IDI: https://twitter.com/kiwiskiNZ/status/1133595698929098752 Assessing the performance of prediction models: a framework for traditional and novel measures. https://www.ncbi.nlm.nih.gov/pubmed/20010215/ Net Reclassification Indices for Evaluating Risk-Prediction Instruments: A Critical Review https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918180/ Predicting Progression in CKD: Perspectives and Precautions https://www.ajkd.org/article/S0272-6386(15)01413-4/abstract The Article by Nancy Cook in Circulation that Jennie was talking about: Use and misuse of the receiver operating characteristic curve in risk prediction. https://www.ncbi.nlm.nih.gov/pubmed/17309939 Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens https://www.nature.com/articles/ng.3118 Genome-wide polygenic risk predictors for kidney disease https://www.nature.com/articles/s41581-018-0067-6 Where does Matt find minutia like the grams of IgA produced a day? Here: https://www.annualreviews.org/doi/abs/10.1146/annurev-pathol-011110-130216 Animal models of IgA nephropathy: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337240/ Matt’s Book Originals: https://www.amazon.com/gp/product/014312885X/ref=dbs_a_def_rwt_bibl_vppi_i1 Eric Neilson, Dean of Northwestern University https://www.feinberg.northwestern.edu/faculty-profiles/az/profile.html?xid=23239 Brussels sprout Insta-famous dog and future dean of the medical school: https://www.instagram.com/brussels.sprout/?hl=en Josh Farkas Rantorial about Contrast Nephropathy: https://twitter.com/PulmCrit/status/1134922050794139648 Swapnil’s Tweetorial about Contrast Nephropathy: https://twitter.com/hswapnil/status/1133906398096609280 Tukaram’s pic of NEJM’s progression from Contrast Induced Nephropathy to Contrast Associated Nephropathy: https://twitter.com/tukaramj/status/1135214980985266178 Zero sodium dialysate for heart failure? https://twitter.com/i/moments/1134811009217155072