Freely Filtered 033: The Roxadustat Statistics shenanigans episode artwork

EPISODE · Apr 20, 2021 · 1H 7M

Freely Filtered 033: The Roxadustat Statistics shenanigans

from Freely Filtered, a NephJC Podcast · host joel topf

Episode metadata supplied by the publisher feed · Published Apr 20, 2021

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On April 6, 2021 Fibrogen announced that the analysis of the cardiovascular outcomes was adjusted after the data was unblinded. When the data was reanalyzed without this adjustment roxadustat is less impactful. Importantly for this NephJC discussion, the previously impressive MACE and MACE+ advantage for incident dialysis is no longer found. Roxadustat remains non-inferior in all outcomes, though the confidence intervals have widened.

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Freely Filtered 033: The Roxadustat Statistics shenanigans

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