Friday Coffee Talk (8/21/26)

LISTENER DISCRETION IS ADVISED! References: Alam N, Oskam E, et. al. PHANTASi Trial Investigators and the ORCA (Onderzoeks Consortium Acute Geneeskunde) Research Consortium the Netherlands. Prehospital antibiotics in the ambulance for sepsis: a multicentre, open label, randomised trial. Lancet Respir Med. 2018 Jan;6(1):40-50. Jouffroy, R., Annane, D., et. al. (2026). A 1-hour resuscitation bundle for prehospital management of septic shock. Critical Care Medicine. Knack, S. K. S., Scott, N., Driver, B. E., et al. (2024). Early physician gestalt versus usual screening tools for the prediction of sepsis in critically ill emergency patients. Annals of Emergency Medicine. Kotnarin R, Sirinawee P, Supasaovapak J. Impact of Prehospital Antibiotics on in-Hospital Mortality in Emergency Medical Service Patients with Sepsis. Open Access Emerg Med. 2023 May 26;15:199-206. Poynter, M. J., Farrugia, A., Kelly, E., & Simpson, P. M. (2023). Prehospital administration of antibiotics in addition to usual care versus usual care alone for patients with suspected sepsis – A systematic review. Paramedicine, 21, 52–65. Scales DC, et. al. Prehospital antibiotics and intravenous fluids for patients with sepsis: protocol for a 2×2 factorial randomised controlled trial. BMJ Open. 2025 May 27;15(5):e104257.