From Genotype to Action: Managing Dual-Deficient Alpha-1

In this episode of Lung Health Champion, host Amanda Atkinson speaks with Dr. Kyle Hogarth about what happens after identifying a severe genotype in alpha-1 antitrypsin deficiency. They outline a practical approach to patient care, including establishing baselines, determining disease risk, and guiding treatment decisions. The discussion covers monitoring strategies, recognizing signs of disease progression, and when to consider augmentation therapy or specialist referral. Dr. Hogarth also addresses common gaps in diagnosis and emphasizes the importance of routine testing and structured follow-up to improve patient outcomes. This episode is proudly supported by Grifols. Find out more here. COPD Foundation: https://www.copdfoundation.org Alpha-1 Foundation: https://www.alpha1.org Dr. Kyle Hogarth on LinkedIn: https://www.linkedin.com/in/d-kyle-hogarth-md-fccp-5a093b1/ Production and editing by The Podcast Consultant: https://thepodcastconsultant.com Order free Alpha-1 testing kits: https://www.alphaid.com/en/hcp/order-free-alphaid-screening-test-kits The receipt of this free testing service does not create any expectation or obligation on your part to purchase or use any product or service offered by any manufacturer. Sign up for COPD Foundation's Newsletter: https://www.copdfoundation.org/About-Us/Who-We-Are/Contact-Us.aspx#enewsletter The podcast is provided by the COPD Foundation as an educational resource only and should not be considered as offering medical advice. This information should not be used as a substitute for a physician's professional judgment in providing advice, diagnosis, or treatment for any medical or health condition. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment before undertaking a new health care regimen. Do not disregard professional medical advice or delay in seeking it because of something you have heard on this podcast.