From Trials to Triumph: 2024’s FDA approvals

Join us this week for a brief tour of some body systems as we review five medications approved by the FDA in 2024. From liver disease to Alzheimer’s, we look at Rezdiffra, Iqirvo, Vafseo, Entyvio, and Kisunla, exploring the diseases they intend to treat and a brief overview of how the medicines work. We celebrate the hard work of volunteers, investigators, coordinators, and other participants in the clinical trial process.Share with a friend. Rate, Review, and Subscribe to MedEvidence! Articles to be notified when new episodes are released.Follow us on Social Media:FacebookInstagramTwitterLinkedInTiktokYoutubeFor more great content, including discussions by physicians and clinical research experts, check out the MedEvidence! podcast. www.MedEvidence.comThank you for listening!References:Akebia Therapeutics, Inc. (27 March, 2024). Akebia receives FDA approval of Vafseo®... PR Newswire. LinkChertow, G. M. et al. (2021). Vadadustat in patients with anemia... New England Journal of Medicine, 384(17), 1589-1600. LinkHarrison, S. A. et al. (2024). A phase 3, randomized, controlled trial of resmetirom in NASH with liver fibrosis. New England Journal of Medicine, 390(6), 497-509. LinkIpsen. (10 June, 2024). Ipsen’s Iqirvo® receives U.S. FDA accelerated approval... LinkJayaprakash, N., & Elumalai, K. (2024). Translational Medicine in Alzheimer's Disease: The Journey of Donanemab From Discovery to Clinical Application. Chronic Diseases and Translational Medicine.  LinkKowdley, K. V. et al. (2024). Efficacy and safety of elafibranor in primary biliary cholangitis. New England Journal of Medicine, 390(9), 795-805. LinkMadrial Pharmaceuticals, Inc. (14 March, 2024). Madrigal pharmaceuticals announces FDA approval of Rezdiffra™... LinkTakeda. (18 April, 2024). U.S. FDA approves subcutaneous administration of Takeda’s ENTYVIO®... LinkU.S. Food and Drug Administration. (7 January, 2025). Novel Drug Approvals for 2024. LinkWyant, T., et al. (2016). An overview of the mechanism of action of the monoclonal antibody vedolizumab. Journal of Crohn's and Colitis, 10(12), 1437-1444. LinkShare with a friend. Rate, Review, and Subscribe to MedEvidence! Articles to be notified when new episodes are released.Follow us on Social Media:FacebookInstagramTwitterLinkedInTiktokYoutubeFor more great content, including discussions by physicians and clinical research experts, check out the MedEvidence! Podcast and MedEvidence.comThank you for listening!