Frontal Lobe Neurobiology, Imaging, and Criminal Patterns: Integrating Prefrontal Dysfunction with Forensic Phenotypes

This article synthesizes evidence linking prefrontal cortex (PFC) structure, function, and connectivity to criminal patterns. It outlines key PFC subregions, neuroimaging methods, recurring imaging signatures found in offender samples, behavioral phenotypes that emerge from prefrontal dysfunction, and the practical, clinical, and legal implications of using frontal‑lobe imaging in forensic contexts. The piece concludes with ethical cautions and research recommendations for more responsible, translational work.