Functional - Piriform Cortex Resection and Seizure Control in TLE

In this episode, we delve into the findings of a study published in the Journal of Neurology in 2026, examining the role of piriform cortex subregion resection in achieving seizure freedom for patients with temporal lobe epilepsy. This full-text review analyzes data from two distinct cohorts, evaluating the direct correlation between resecting specific piriform cortex areas and the long-term absence of seizures. The key findings indicate no significant link between these targeted resections and improved seizure control, prompting a re-evaluation of surgical strategies for drug-resistant epilepsy. Join us as we discuss the implications of this research for clinical practice. This content is for informational purposes only and does not constitute medical advice.