Functional - Piriform Cortex Resection and Seizure Outcomes in TLE

In this episode, we delve into the findings of a study published in the Journal of Neurology in 2026, examining the relationship between piriform cortex subregion resection and seizure freedom in patients with temporal lobe epilepsy. The full text article investigated two distinct patient cohorts to assess the impact of resecting specific areas of the piriform cortex on long-term seizure control. The key findings indicate no significant association between these resections and achieving seizure freedom, challenging previous assumptions. This discussion is crucial for neurosurgeons and epileptologists considering surgical targets for refractory epilepsy. This content is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare professional for any health concerns or before making any decisions related to your health or treatment.