Gabe Charalambides: Psilocybin-Assisted Therapy, Anxiety Relief, and Healing Trauma Through Safe, Evidence-Based Retreats

Gabe Charalambides is the founder of Odyssey, the world’s leading provider of psilocybin-assisted therapy, and a Stanford-trained aerospace engineer whose personal experience with anxiety helped shape a mission: making psychedelic healing safer, more responsible, and more accessible to everyday people. After years working alongside leading psychedelic organizations, Gabe launched Odyssey in 2023 and helped open the first legal psilocybin retreat in the U.S., rooted in screening, preparation, and evidence-based support.In this conversation, we explore what psilocybin therapy can look like when done responsibly—why education, intention-setting, and integration matter as much as the ceremony itself. Gabe explains how psilocybin may reduce mental rigidity, increase psychological flexibility, and help people move through trauma, rumination, and fear—especially the existential distress that can come with a cancer diagnosis. We also break down what a guided experience typically involves (screening, preparation sessions, a full-day facilitated journey, and post-session integration), what outcomes Odyssey is tracking through an IRB-approved study, and why many participants describe their experience as one of the most meaningful of their lives.If you’ve been curious about psychedelics but unsure what “safe” really means—or you’re navigating chronic illness, anxiety, or trauma and looking for new tools—this episode offers a grounded, practical look at what’s real, what’s promising, and what to consider before taking the next step. To learn more, visit https://www.odysseypbc.com/Key Topics CoveredGabe’s background: Stanford-trained aerospace engineer → founder of OdysseyHow anxiety, OCD, and meditation shaped his approach to mental healthWhy psilocybin can help “unstick” rigid thought patterns and emotional loopsWhat a safe, legal psilocybin-assisted therapy process looks like (screening → prep → session → integration)“Set and setting” explained: why environment and support dramatically change outcomesSpiritual and psychological effects people commonly report (connection, meaning, reduced fear of death)Microdosing vs. full-dose therapy: differences, evidence, and expectationsSafety considerations: contraindications, unpleasant experiences, and why support mattersOdyssey’s IRB-approved outcomes study and what they’re measuring (wellbeing, anxiety, flexibility, mindfulness)How this work may support cancer patients facing existential distress and fear ____________________________________RESOURCES FROM DR. KARLFELDT:📖 A Better Way to Treat Cancer: A Comprehensive Guide to Understanding, Preventing and Most Effectively Treating Our Biggest Health ThreatGet it on Amazon: https://a.co/d/0iC8bFxy📖 Unleashing 10X Power: A Revolutionary Approach to Conquering CancerGet it here: store.thekarlfeldtcenter.com/products/unleashing-10x-powerPrice: $24.99 | Use code CANCERPODCAST1 for 100% off📖 Healing Within: Unraveling the Emotional Roots of CancerGet it here: store.thekarlfeldtcenter.com/products/healing-withinPrice: $24.99 | Use code CANCERPODCAST2 for 100% off____________________________________WORK WITH DR. KARLFELDT:To learn more about cutting-edge integrative cancer therapies at The Karlfeldt Center or to schedule a free 15-minute consultation, visit us at:🌐 TheKarlfeldtCenter.com📞 208-338-8902📧 [email protected]____________________________________CONNECT WITH DR. KARLFELDT:Instagram: instagram.com/thekarlfeldtcenterFacebook: facebook.com/thekarlfeldtcenter____________________________________MORE PODCASTS FROM DR. KARLFELDT:🎙 The Dr. K Show — Integrative medicine, functional medicine,  biohacking, and longevity for optimizing health and performance.🎙 Integrative Lyme Solutions — Expert guidance and healing journeys  for those dealing with Lyme disease and co-infections.Explore all shows at https://www.youtube.com/@karlfeldtcenter____________________________________👉 Schedule a Free 15-Minute Discovery Call with a Naturopathic Doctor at The Karlfeldt Center:📞 208-338-8902📧 [email protected]