Gastro: Caecal Carcinoma: Free MSRA Podcast

⚕️ FREE MSRA PODCAST – Caecal Carcinoma🎧 A clear, high-yield breakdown of this right-sided colorectal cancer subtype – perfect for exam prep and real-life clinicalscenarios. 🧠 Key Learning Points📌 Definition•Caecal Carcinoma is a malignant tumour arising from the caecum – the first partof the colon – and is a subtype of colorectal cancer. Often presents withsubtle or late-stage symptoms.📌 Causes & Risk Factors•Age >50•Family history of colorectal cancer or polyps•Inflammatory bowel disease (Crohn’s, UC)•Diet: High red/processed meat, low fibre•Obesity, smoking, alcohol•Genetic syndromes: Lynch syndrome, FAP•Previous colorectal cancer or polyps🧠 Mnemonic: AFIDONGAP – Age, Familyhistory, IBD, Diet, Obesity, Neoplastic polyps, Genetics, Alcohol, Previouscancer📌 Pathophysiology•Starts with adenomatous polyp →accumulates genetic mutations → becomes malignanttumour•Spreads locally to tissues, lymph nodes, and potentially to distant organs(e.g., liver, lungs)🧠 Think: Polyp = seed, Invasion =roots📌 Symptoms•Right iliac fossa pain•Iron-deficiency anaemia (from occultbleeding)•Change in bowel habits (diarrhoea orconstipation)•Fatigue, weight loss, palpable mass•Sometimes mimics appendicitis or presentswith bowel obstruction/perforation📌 Differential Diagnosis•Other right-sided colorectal cancers•Diverticulitis•Crohn’s disease / Ulcerative colitis•Gastrointestinal stromal tumour (GIST)•Benign caecal polyps or lesions📌 Diagnosis•Screening: FOB test (ages 60–75),flexible sigmoidoscopy at age 55•Investigations:–Colonoscopy with biopsy–Full blood count: microcytic anaemia–CT abdomen/pelvis for staging–CEA tumour marker (for monitoring, notdiagnosis)🧠 Mnemonic: “See + Stage” –Colonoscopy + CT📌 Management•Urgent referral via NICE 2-week criteria(e.g., rectal bleeding, anaemia, mass)•Surgery: Right hemicolectomy with lymphnode resection•Adjuvant chemotherapy (Stage III and somehigh-risk Stage II) – FOLFOX regimen•Biological therapies in advanced cases(e.g., bevacizumab)•Surgical resection of metastases (e.g.,liver) in selected patients📌 Complications•Bowel obstruction or perforation•Recurrent disease•Metastasis (liver, lungs)•Bleeding, anaemia•Nutritional deficiencies•Side effects from treatment (surgery,chemo)📌 Prognosis•Depends on stage at diagnosis, patient age, and overallhealth•Early-stage cancers have significantlybetter outcomes•Regular follow-up is essential for recurrence monitoring 📎 More MSRA Resources for CaecalCarcinoma📝 Revision Notes: https://www.passthemsra.com/topic/caecal-carcinoma-revision-notes/🧠 Flashcards: https://www.passthemsra.com/topic/caecal-carcinoma-flashcards/💬 Accordion Q&A Notes: https://www.passthemsra.com/topic/caecal-carcinoma-accordion-qa-notes/🚀 Rapid Quiz: https://www.passthemsra.com/topic/caecal-carcinoma-rapid-quiz/🎓 Full Course: https://www.passthemsra.com/courses/gastroenterology-for-the-msra/ Hashtags#MSRA#MSRARevision #MSRATextbook #MSRAQuiz #MSRAQuestionBank #MSRAFlashcards#MSRAQ&ANotes #MSRAAccordions #MultiSpecialtyRecruitmentAssessment#MSRAOnlineRevision #MSRARevisionWebsite #CaecalCarcinoma