EPISODE · May 18, 2025 · 18 MIN
Gastro: GORD: Free MSRA Podcast
from Pass the MSRA: Free Podcasts · host Pass the MSRA
⚕️FREE MSRA PODCAST –GORD🎧 A comprehensive revision session on Gastro-Oesophageal Reflux Disease, packed with memory tips, clinical insights, andUK-based exam relevance. 🧠Key Learning Points📌Definition• GORD(Gastro-Oesophageal Reflux Disease) is a chroniccondition where stomach acid repeatedlyflows back into the oesophagus, irritating its lining.• Caused bydysfunction of the lower oesophageal sphincter(LOS), allowing acid reflux. 📌Causes & RiskFactors• Common causes:Weak or relaxed LOSDelayed gastric emptyingObesityHiatus herniaSmokingPregnancyCertain medications (e.g., CCBs, nitrates, TCAs)Diet: caffeine, alcohol, chocolate, fatty foods💡Mnemonic: OBESADE –Obesity, Bad habits (smoking, alcohol), Eating large meals, Scleroderma,Ageing, Drugs (CCBs, nitrates), Expecting (pregnancy) 📌Pathophysiology• LOS fails → acidrefluxes up• Acid damagesoesophageal lining → oesophagitis• Chronicinflammation may lead to ulcers, strictures, or Barrett’soesophagus (a pre-cancerous state) 📌Symptoms• Classic:Heartburn (burning chest pain post-meals)Acid regurgitationChest discomfort• Atypical:Chronic coughHoarseness (Cherry Doner Syndrome)Asthma-like symptomsEpigastric pain 📌DifferentialDiagnosis• Angina• Peptic ulcers• Non-ulcerdyspepsia• Oesophageal cancer• Motility disorders• Infectiousoesophagitis (CMV, candida, HSV)• Oesophageal spasm 📌Diagnosis• Often clinical, based on symptoms and trial of PPIs• Further tests if:Symptoms persistRed flags (dysphagia, anaemia, weight loss)Patient is over 55 • Investigations:Endoscopy (OGD)24-hour pH monitoring (gold standard)ManometryBarium swallowFBC for anaemia💡Remember: symptomsdon’t always correlate with severity on endoscopy 📌Management• Lifestyle changes (first-line):Weight lossAvoid trigger foodsElevate head of bedAvoid eating lateStop smoking/alcohol• Medications:PPIs (e.g., omeprazole) – 4–8 week trialStep-down to lowest effective doseAdd H2 blockers (e.g., ranitidine) if neededAvoid long-term use unless clearly indicated• Surgical:Fundoplication – for refractory GORDNewer: LINX magnetic bead device (less common)💡Take PPIs 30–60 minsbefore breakfast for best effect 📌Complications• Oesophagitis• Oesophagealstrictures• Barrett’soesophagus• Oesophagealadenocarcinoma• Dental erosion• Iron-deficiencyanaemia• Globus sensation• Reflux-relatedchronic cough/asthma 📌Prognosis• Excellent with proper management• Requires long-term lifestyle changes• Monitoringessential for Barrett’s or chronicsymptoms• Failure to managecan lead to significant morbidity 📎More MSRA Resourcesfor GORD📝 Revision Notes:https://www.passthemsra.com/topic/gastroesophageal-reflux-disease-gord-revision-notes/🧠 Flashcards:https://www.passthemsra.com/topic/gastroesophageal-reflux-disease-gord-flashcards/💬 Accordion Q&A Notes:https://www.passthemsra.com/topic/gastroesophageal-reflux-disease-gord-accordion-qa-notes/🚀 Rapid Quiz:https://www.passthemsra.com/topic/gastroesophageal-reflux-disease-gord-rapid-quiz/🎓 Full Course:https://www.passthemsra.com/courses/gastroenterology-for-the-msra/ Hashtags#MSRA #MSRARevision#MSRATextbook #MSRAQuiz #MSRAQuestionBank #MSRAFlashcards #MSRAQ&ANotes#MSRAAccordions #MultiSpecialityRecruitmentAssessment #MSRAOnlineRevision#MSRARevisionWebsite #GORD
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Gastro: GORD: Free MSRA Podcast
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