GENERAL MEDICINE: Vaginal Progesterone Reduced Risk of Preterm Birth in Women with Short Cervix

Audio Journal of Medicine, August 23rd 2007 Vaginal Progesterone Reduced Risk of Preterm Birth in Women with Short Cervix REFERENCE: N Engl J Med 2007; 357: 426-9 KYPROS NICOLAIDES, Kings College Hospital, London The risk of giving birth prematurely was reduced among pregnant women with short cervices by treatment with vaginally administered progesterone: whether or not they had a history of preterm delivery. Investigators from London have reported in the New England Journal of Medicine that progesterone therapy significantly reduced the risk of spontaneous delivery before 34 weeks: from a one in three chance with a placebo to one in five with progesterone. Kypros Nicolaides discussed the results with Anna Lacey.